Jong-chan Park
Seoul, Republic of Korea
Last Updated: 09/26/2026
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Found 13 publications
Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer.
Journal: Experimental & molecular medicine
Published: March 03, 2020
5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation.
Journal: Nature communications
Published: September 09, 2019
A mutant KRAS-induced factor REG4 promotes cancer stem cell properties via Wnt/β-catenin signaling.
Journal: International journal of cancer
Published: June 17, 2019
WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer.
Journal: Cell communication and signaling : CCS
Published: June 10, 2019
WDR76 mediates obesity and hepatic steatosis via HRas destabilization.
Journal: Scientific reports
Published: February 22, 2019
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.
Journal: Nature communications
Published: May 23, 2018
Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling.
Journal: Experimental & molecular medicine
Published: February 19, 2018
KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer.
Journal: Oncotarget
Published: August 20, 2016
Sur8 mediates tumorigenesis and metastasis in colorectal cancer.
Journal: Experimental & molecular medicine
Published: December 23, 2015
Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development.
Journal: Journal of cell science
Published: December 04, 2015
Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling.
Journal: Oncotarget
Published: June 02, 2015
K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis.
Journal: Oncotarget
Published: February 27, 2015
Last Updated: 09/26/2026