Joo-youn Lee

Daejeon, Republic of Korea

Last Updated: 09/26/2026

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Found 53 publications

Discovery and Pharmacological Characterization of a Dual-Acting 2-Amino-3-Cyanopyridine Inhibitor Targeting Microtubule Polymerization and GAK.

Discovery and Pharmacological Characterization of a Dual-Acting 2-Amino-3-Cyanopyridine Inhibitor Targeting Microtubule Polymerization and GAK.

Journal: Journal of medicinal chemistry

Published: June 16, 2026

Discovery of a New Tetrahydroquinoline-Based Chemotype for STING Inhibition with In Vivo Efficacy against Acute Kidney Injury.

Discovery of a New Tetrahydroquinoline-Based Chemotype for STING Inhibition with In Vivo Efficacy against Acute Kidney Injury.

Journal: Journal of medicinal chemistry

Published: April 18, 2026

Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress-induced cytotoxicity.

Predicted molecules followed by experimental validation for protecting human neurons from oxidative stress-induced cytotoxicity.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 03, 2025

Development and Evaluation of 1‑Hydroxypyridin-2(1H)‑one Derivatives as Antibacterial Agents against Pathogenic Pseudomonas aeruginosa.

Development and Evaluation of 1‑Hydroxypyridin-2(1H)‑one Derivatives as Antibacterial Agents against Pathogenic Pseudomonas aeruginosa.

Journal: ACS medicinal chemistry letters

Published: September 19, 2025

2-amido-3-aryl-4-methyl-thiazole derivatives as broad-spectrum anti-rhinoviral agents.

2-amido-3-aryl-4-methyl-thiazole derivatives as broad-spectrum anti-rhinoviral agents.

Journal: European journal of medicinal chemistry

Published: September 09, 2025

Critical amino acid residues in human ACE2 for SARS-CoV-2 spike protein binding and virus entry.

Critical amino acid residues in human ACE2 for SARS-CoV-2 spike protein binding and virus entry.

Journal: Microbiology spectrum

Published: June 20, 2025

Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities.

Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities.

Journal: Frontiers in pharmacology

Published: June 11, 2025

Discovery of novel WRN inhibitors for treating MSI-H colorectal cancers.

Discovery of novel WRN inhibitors for treating MSI-H colorectal cancers.

Journal: Bioorganic & medicinal chemistry letters

Published: January 06, 2025

Blocking S1P4 signaling attenuates brain injury in mice with ischemic stroke.

Blocking S1P4 signaling attenuates brain injury in mice with ischemic stroke.

Journal: Journal of advanced research

Published: September 29, 2024

Edeine B1 produced by Brevibacillus brevis reduces the virulence of a plant pathogenic fungus by inhibiting mitochondrial respiration.

Edeine B1 produced by Brevibacillus brevis reduces the virulence of a plant pathogenic fungus by inhibiting mitochondrial respiration.

Journal: mBio

Published: June 11, 2024

Correction: Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents.

Correction: Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents.

Journal: RSC medicinal chemistry

Published: May 21, 2024

7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication.

7-Amino-3-phenyl-2-methyl-pyrazolopyrimidine derivatives inhibit human rhinovirus replication.

Journal: European journal of medicinal chemistry

Published: May 14, 2024

Showing 1-12 of 53

Last Updated: 09/26/2026