Jorg J. Mohrle

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 68 publications

Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum.

Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum.

Journal: Science translational medicine
Published: November 26, 2025

Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study.

Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study.

Journal: PLoS computational biology
Published: September 04, 2025

A roadmap for understanding sulfadoxine-pyrimethamine in malaria chemoprevention.

A roadmap for understanding sulfadoxine-pyrimethamine in malaria chemoprevention.

Journal: Parasitology
Published: January 23, 2025

Therapeutic development to accelerate malaria control through intentional intervention layering.

Therapeutic development to accelerate malaria control through intentional intervention layering.

Journal: Malaria journal
Published: October 16, 2024

Public health impact of current and proposed age-expanded perennial malaria chemoprevention: a modelling study.

Public health impact of current and proposed age-expanded perennial malaria chemoprevention: a modelling study.

Journal: Scientific reports
Published: September 18, 2024

PBPK-Led Assessment of Antimalarial Drug Concentrations in Breastmilk: A Strategy for Optimal Use of Prediction Methods to Guide Decision Making in an Understudied Population.

PBPK-Led Assessment of Antimalarial Drug Concentrations in Breastmilk: A Strategy for Optimal Use of Prediction Methods to Guide Decision Making in an Understudied Population.

Journal: CPT: pharmacometrics & systems pharmacology
Published: August 29, 2024

How long does it take to develop a new drug?

How long does it take to develop a new drug?

Journal: The Lancet regional health. Europe
Published: June 21, 2024

Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure.

Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure.

Journal: Malaria journal
Published: May 02, 2024

Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria.

Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria.

Journal: BMC medicine
Published: March 07, 2024

PBPK-led assessment of antimalarial drugs as candidates for Covid-19: Simulating concentrations at the site of action to inform repurposing strategies.

PBPK-led assessment of antimalarial drugs as candidates for Covid-19: Simulating concentrations at the site of action to inform repurposing strategies.

Journal: Clinical and translational science
Published: December 12, 2023

Using Cryopreserved Plasmodium falciparum Sporozoites in a Humanized Mouse Model to Study Early Malaria Infection Processes and Test Prophylactic Treatments.

Using Cryopreserved Plasmodium falciparum Sporozoites in a Humanized Mouse Model to Study Early Malaria Infection Processes and Test Prophylactic Treatments.

Journal: Microorganisms
Published: July 11, 2023

Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.

Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.

Journal: Antimicrobial agents and chemotherapy
Published: May 03, 2023
Showing 1-12 of 68

Last Updated: 09/26/2026