Jorge J. Velarde

Pediatric Infectious Disease
300 Longwood Ave
Boston, MA 02115

Last Updated: 09/26/2026

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Found 9 publications

SLO co-opts host cell glycosphingolipids to access cholesterol-rich lipid rafts for enhanced pore formation and cytotoxicity.

SLO co-opts host cell glycosphingolipids to access cholesterol-rich lipid rafts for enhanced pore formation and cytotoxicity.

Journal: mBio
Published: January 21, 2025

Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability.

Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability.

Journal: Nature communications
Published: August 16, 2022

Streptococcus pyogenes can support or inhibit growth of Haemophilus influenzae by supplying or restricting extracellular NAD.

Streptococcus pyogenes can support or inhibit growth of Haemophilus influenzae by supplying or restricting extracellular NAD.

Journal: PloS one
Published: February 14, 2022

Structure of the Streptococcus pyogenes NAD+ Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes.

Structure of the Streptococcus pyogenes NAD+ Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes.

Journal: Journal of bacteriology
Published: October 25, 2021

RocA Binds CsrS To Modulate CsrRS-Mediated Gene Regulation in Group A Streptococcus.

RocA Binds CsrS To Modulate CsrRS-Mediated Gene Regulation in Group A Streptococcus.

Journal: mBio
Published: July 18, 2019

Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.

Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.

Journal: mBio
Published: March 08, 2018

Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus.

Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus.

Journal: mBio
Published: September 14, 2017

NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.

NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.

Journal: PLoS pathogens
Published: January 11, 2016

The human antimicrobial peptide LL-37 binds directly to CsrS, a sensor histidine kinase of group A Streptococcus, to activate expression of virulence factors.

The human antimicrobial peptide LL-37 binds directly to CsrS, a sensor histidine kinase of group A Streptococcus, to activate expression of virulence factors.

Journal: The Journal of biological chemistry
Published: November 08, 2014
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Last Updated: 09/26/2026