Jose A. Silva

Cp 11101
Belem, PA 66075110, Brazil

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 28 publications

Ligand-based design and synthesis of novel 3-spiro-2-oxindoline derivatives as potent VEGFR-2 inhibitors with antiproliferative activity and cell cycle arrest.

Ligand-based design and synthesis of novel 3-spiro-2-oxindoline derivatives as potent VEGFR-2 inhibitors with antiproliferative activity and cell cycle arrest.

Journal: Bioorganic chemistry

Published: June 09, 2026

Conformational Dynamics and Binding Interactions of SARS-CoV-2 Spike Protein Variants: Omicron, XBB.1.9.2, and EG.5.

Conformational Dynamics and Binding Interactions of SARS-CoV-2 Spike Protein Variants: Omicron, XBB.1.9.2, and EG.5.

Journal: Journal of chemical information and modeling

Published: July 11, 2025

Navigating the complexities of drug development for metallo-β-lactamase inhibitors.

Navigating the complexities of drug development for metallo-β-lactamase inhibitors.

Journal: RSC medicinal chemistry

Published: January 14, 2025

Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer.

Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer.

Journal: Scientific reports

Published: June 30, 2024

LDH-Indomethacin Nanoparticles Antitumoral Action: A Possible Coadjuvant Drug for Cancer Therapy.

LDH-Indomethacin Nanoparticles Antitumoral Action: A Possible Coadjuvant Drug for Cancer Therapy.

Journal: Molecules (Basel, Switzerland)

Published: June 06, 2024

Role of UDP-N-acetylmuramic acid in the regulation of MurA activity revealed by molecular dynamics simulations.

Role of UDP-N-acetylmuramic acid in the regulation of MurA activity revealed by molecular dynamics simulations.

Journal: Protein science : a publication of the Protein Society

Published: October 14, 2023

Computational Analysis of Triazole-Based Kojic Acid Analogs as Tyrosinase Inhibitors by Molecular Dynamics and Free Energy Calculations.

Computational Analysis of Triazole-Based Kojic Acid Analogs as Tyrosinase Inhibitors by Molecular Dynamics and Free Energy Calculations.

Journal: Molecules (Basel, Switzerland)

Published: November 04, 2022

Computational Analysis of SAM Analogs as Methyltransferase Inhibitors of nsp16/nsp10 Complex from SARS-CoV-2.

Computational Analysis of SAM Analogs as Methyltransferase Inhibitors of nsp16/nsp10 Complex from SARS-CoV-2.

Journal: International journal of molecular sciences

Published: October 16, 2022

Assessment of host-guest molecular encapsulation of eugenol using β-cyclodextrin.

Assessment of host-guest molecular encapsulation of eugenol using β-cyclodextrin.

Journal: Frontiers in chemistry

Published: October 05, 2022

In Silico Study towards Repositioning of FDA-Approved Drug Candidates for Anticoronaviral Therapy: Molecular Docking, Molecular Dynamics and Binding Free Energy Calculations.

In Silico Study towards Repositioning of FDA-Approved Drug Candidates for Anticoronaviral Therapy: Molecular Docking, Molecular Dynamics and Binding Free Energy Calculations.

Journal: Molecules (Basel, Switzerland)

Published: July 29, 2022

Metabolic Processing of Selenium-Based Bioisosteres of meso-Diaminopimelic Acid in Live Bacteria.

Metabolic Processing of Selenium-Based Bioisosteres of meso-Diaminopimelic Acid in Live Bacteria.

Journal: Biochemistry

Published: June 10, 2022

Exploring the Catalytic Mechanism of the RNA Cap Modification by nsp16-nsp10 Complex of SARS-CoV-2 through a QM/MM Approach.

Exploring the Catalytic Mechanism of the RNA Cap Modification by nsp16-nsp10 Complex of SARS-CoV-2 through a QM/MM Approach.

Journal: International journal of molecular sciences

Published: November 01, 2021

Showing 1-12 of 28

Last Updated: 09/26/2026