Jose L. Rosa
Barcelona, CT, Spain
Last Updated: 09/26/2026
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Found 63 publications
Proteasome dysfunction underlies HERC2-linked neurodevelopmental disorder with Angelman-like clinical features.
Journal: Cell death discovery
Published: January 26, 2026
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification.
Journal: eLife
Published: June 17, 2025
Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder.
Journal: Cell death discovery
Published: January 09, 2024
Regulation of Ubiquitin Family Signaling in Disease.
Journal: International journal of molecular sciences
Published: March 28, 2023
Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases.
Journal: International journal of molecular sciences
Published: January 30, 2023
Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: July 12, 2022
HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling.
Journal: Cell death & disease
Published: June 07, 2022
HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress.
Journal: Cellular and molecular life sciences : CMLS
Published: April 27, 2022
The HERC proteins and the nervous system.
Journal: Seminars in cell & developmental biology
Published: September 21, 2021
NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression.
Journal: Redox biology
Published: November 30, 2020
HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory.
Journal: Frontiers in neuroanatomy
Published: August 08, 2020
A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism.
Journal: Molecular genetics and metabolism
Published: June 17, 2020
Last Updated: 09/26/2026