Jose M. Cumella

Madrid, MD, Spain

Last Updated: 09/26/2026

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Found 12 publications

Direct amidinium-phosphate interactions guide AT-selective DNA binding by a potent antileishmanial drug.

Direct amidinium-phosphate interactions guide AT-selective DNA binding by a potent antileishmanial drug.

Journal: Communications chemistry

Published: November 24, 2025

Spiranic compounds as novel AMPK paradoxical inhibitors: can we derive new mechanistic insights?

Spiranic compounds as novel AMPK paradoxical inhibitors: can we derive new mechanistic insights?

Journal: European journal of medicinal chemistry

Published: September 13, 2025

Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis.

Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis.

Journal: CNS neuroscience & therapeutics

Published: February 13, 2023

Deciphering the Myrosinase-like Activity of Lactiplantibacillus plantarum WCFS1 among GH1 Family Glycoside Hydrolases.

Deciphering the Myrosinase-like Activity of Lactiplantibacillus plantarum WCFS1 among GH1 Family Glycoside Hydrolases.

Journal: Journal of agricultural and food chemistry

Published: December 01, 2022

Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease.

Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease.

Journal: ACS chemical neuroscience

Published: December 28, 2021

Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK-eNOS-NO pathway.

Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK-eNOS-NO pathway.

Journal: Scientific reports

Published: June 15, 2021

Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies.

Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies.

Journal: Parasitology

Published: June 13, 2020

N-benzyl 4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction.

N-benzyl 4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction.

Journal: European journal of medicinal chemistry

Published: February 04, 2020

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.

Journal: ChemMedChem

Published: February 08, 2018

Structural basis of the substrate specificity and instability in solution of a glycosidase from Lactobacillus plantarum.

Structural basis of the substrate specificity and instability in solution of a glycosidase from Lactobacillus plantarum.

Journal: Biochimica et biophysica acta. Proteins and proteomics

Published: April 07, 2017

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.

Journal: European journal of medicinal chemistry

Published: November 23, 2015

Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties.

Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties.

Journal: ChemMedChem

Published: November 30, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026