Last Updated: 09/26/2026
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Found 10 publications
A first-in-human, Phase 1/2a, open-label study of SQ3370, a first-in-class doxorubicin-based click chemistry therapeutic, in patients with advanced solid tumors.
Journal: medRxiv : the preprint server for health sciences
Published: June 12, 2025
Development of a First-in-Class Click Chemistry-Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: August 06, 2024
SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species.
Journal: bioRxiv : the preprint server for biology
Published: April 10, 2023
Correction: Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation.
Journal: Chemical science
Published: June 24, 2021
Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation.
Journal: Chemical science
Published: June 24, 2021
Titanium coating with mussel inspired polymer and bio-orthogonal chemistry enhances antimicrobial activity against Staphylococcus aureus.
Journal: Materials science & engineering. C, Materials for biological applications
Published: February 12, 2020
Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections.
Journal: ACS central science
Published: May 30, 2018
Implantable biomaterial based on click chemistry for targeting small molecules.
Journal: Acta biomaterialia
Published: May 06, 2014
Showing 1-10 of 10
Last Updated: 09/26/2026