Jose M. Zapico
Boadilla Del Monte, MD, Spain
Last Updated: 09/26/2026
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Found 23 publications
Chronic inhibition of receptor protein tyrosine phosphatase β/ζ reduces amyloid plaque load and modulates pleiotrophin-expressing glial cells, glial-plaque interactions and genes related to amyloid beta clearance.
Journal: Frontiers in pharmacology
Published: March 26, 2026
Pleiotrophin and receptor protein tyrosine phosphatase β/ζ as key modulators of high-fat diet-induced cognitive impairment and brain alterations.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: July 30, 2025
Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice.
Journal: Frontiers in pharmacology
Published: October 04, 2024
A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death, gliosis, and electroretinogram distortion in male rats subjected to perinatal asphyxia.
Journal: Frontiers in pharmacology
Published: July 03, 2023
Implication of the PTN/RPTPβ/ζ Signaling Pathway in Acute Ethanol Neuroinflammation in Both Sexes: A Comparative Study with LPS.
Journal: Biomedicines
Published: December 31, 2022
A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death and electroretinogram distortion in a rat model of intraorbital optic nerve crush (IONC).
Journal: Frontiers in pharmacology
Published: November 30, 2022
Inhibition of RPTPβ/ζ reduces chronic ethanol intake in adolescent mice and modulates ethanol effects on hippocampal neurogenesis and glial responses in a sex-dependent manner.
Journal: Neuropharmacology
Published: October 02, 2022
Receptor protein tyrosine phosphatase β/ζ regulates loss of neurogenesis in the mouse hippocampus following adolescent acute ethanol exposure.
Journal: Neurotoxicology
Published: June 14, 2022
Design and Synthesis of Water-Soluble and Potent MMP-13 Inhibitors with Activity in Human Osteosarcoma Cells.
Journal: International journal of molecular sciences
Published: July 07, 2021
Role of Receptor Protein Tyrosine Phosphatase β/ζ in Neuron-Microglia Communication in a Cellular Model of Parkinson's Disease.
Journal: International journal of molecular sciences
Published: May 21, 2021
Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication.
Journal: Scientific reports
Published: May 21, 2020
Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors.
Journal: Molecules (Basel, Switzerland)
Published: February 28, 2020
Last Updated: 09/26/2026