Josef Jiricny

Zurich, ZH 8093, Switzerland

Last Updated: 09/26/2026

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Found 34 publications

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair.

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair.

Journal: Nature communications
Published: September 06, 2021

FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.

FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.

Journal: Molecular and cellular biology
Published: July 06, 2021

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.

Journal: Science advances
Published: November 19, 2020

TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events.

TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events.

Journal: Nature communications
Published: May 12, 2020

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition.

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition.

Journal: Nucleic acids research
Published: January 23, 2020

Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding.

Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding.

Journal: Molecular and cellular biology
Published: September 12, 2019

Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts.

Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts.

Journal: Nature communications
Published: April 05, 2019

Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.

Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.

Journal: Nucleic acids research
Published: March 01, 2019

Author Correction: FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Author Correction: FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Journal: Nature communications
Published: December 22, 2017

An appreciation of Sir Adrian Peter Bird: winner of the Charles Rodolphe Brupbacher Prize for Cancer Research 2017.

An appreciation of Sir Adrian Peter Bird: winner of the Charles Rodolphe Brupbacher Prize for Cancer Research 2017.

Journal: Swiss medical weekly
Published: October 18, 2017

Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells.

Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells.

Journal: Molecular cell
Published: July 08, 2017

FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Journal: Nature communications
Published: June 24, 2017
Showing 1-12 of 34

Last Updated: 09/26/2026