Joseph A. Leedale
Jeallott's Hill International Research Centre
Bracknell, ENG, United Kingdom
Bracknell, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 18 publications
Translating in vitro buccal permeation to in vivo and whole‑body exposure using in silico cell‑based and physiologically-based pharmacokinetic modelling.
Journal: International journal of pharmaceutics
Published: December 02, 2025
An advanced in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation.
Journal: International journal of pharmaceutics
Published: April 28, 2024
Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration.
Journal: ALTEX
Published: February 15, 2023
A mathematical investigation into the uptake kinetics of nanoparticles in vitro.
Journal: PloS one
Published: December 07, 2020
Mathematical modelling of oxygen gradients in stem cell-derived liver tissue.
Journal: PloS one
Published: September 03, 2020
Multiscale modelling of drug transport and metabolism in liver spheroids.
Journal: Interface focus
Published: November 13, 2019
Preparation of Primary Rat Hepatocyte Spheroids Utilizing the Liquid-Overlay Technique.
Journal: Current protocols in toxicology
Published: September 19, 2019
Modelling changes in glutathione homeostasis as a function of quinone redox metabolism.
Journal: Scientific reports
Published: December 27, 2018
Characterisation of a functional rat hepatocyte spheroid model.
Journal: Toxicology in vitro : an international journal published in association with BIBRA
Published: August 07, 2018
Systems Toxicology Approach to Identifying Paracetamol Overdose.
Journal: CPT: pharmacometrics & systems pharmacology
Published: December 27, 2017
A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity.
Journal: iScience
Published: November 24, 2017
Last Updated: 09/26/2026