Joseph D. Schrag

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 15 publications

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages.

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages.

Journal: The Journal of biological chemistry
Published: June 15, 2023

Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates.

Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates.

Journal: Scientific reports
Published: April 12, 2023

Corrigendum: Structure-guided design of a potent Clostridioides difficile toxin A inhibitor.

Corrigendum: Structure-guided design of a potent Clostridioides difficile toxin A inhibitor.

Journal: Frontiers in microbiology
Published: February 16, 2023

A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens.

A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens.

Journal: Biotechnology and bioengineering
Published: January 17, 2023

Structure-guided design of a potent Clostridiodes difficile toxin A inhibitor.

Structure-guided design of a potent Clostridiodes difficile toxin A inhibitor.

Journal: Frontiers in microbiology
Published: November 28, 2022

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.

Journal: Nature communications
Published: March 08, 2022

Characterization of a SARS-CoV-2 spike protein reference material.

Characterization of a SARS-CoV-2 spike protein reference material.

Journal: Analytical and bioanalytical chemistry
Published: January 11, 2022

Development of a scalable and robust AEX method for enriched rAAV preparations in genome-containing VCs of serotypes 5, 6, 8, and 9.

Development of a scalable and robust AEX method for enriched rAAV preparations in genome-containing VCs of serotypes 5, 6, 8, and 9.

Journal: Molecular therapy. Methods & clinical development
Published: October 17, 2020

Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells.

Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells.

Journal: Journal of biotechnology
Published: September 20, 2020

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment.

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment.

Journal: mAbs
Published: November 29, 2019

Binding symmetry and surface flexibility mediate antibody self-association.

Binding symmetry and surface flexibility mediate antibody self-association.

Journal: mAbs
Published: July 19, 2019

Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System.

Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System.

Journal: Molecular therapy. Methods & clinical development
Published: August 21, 2018
Showing 1-12 of 15

Last Updated: 09/26/2026