Joseph E. Chambers

Hills Rd
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 36 publications

p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver proteotoxicity.

p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver proteotoxicity.

Journal: The Journal of biological chemistry
Published: April 09, 2026

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability.

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: October 27, 2025

FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing.

FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing.

Journal: Nature communications
Published: September 30, 2024

Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency.

Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency.

Journal: Nature genetics
Published: May 20, 2024

Author Correction: Macromolecular condensation buffers intracellular water potential.

Author Correction: Macromolecular condensation buffers intracellular water potential.

Journal: Nature
Published: April 08, 2024

A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies.

A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies.

Journal: The Journal of biological chemistry
Published: March 11, 2024

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport.

Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport.

Journal: Cell reports
Published: February 14, 2024

Enhancing Drug Delivery Efficacy Through Bilayer Coating of Zirconium-Based Metal-Organic Frameworks: Sustained Release and Improved Chemical Stability and Cellular Uptake for Cancer Therapy.

Enhancing Drug Delivery Efficacy Through Bilayer Coating of Zirconium-Based Metal-Organic Frameworks: Sustained Release and Improved Chemical Stability and Cellular Uptake for Cancer Therapy.

Journal: Chemistry of materials : a publication of the American Chemical Society
Published: November 21, 2023

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

Journal: Nature communications
Published: June 22, 2023

Landslide assessment through integrated geoelectrical and seismic methods: A case study in Thungsong site, southern Thailand.

Landslide assessment through integrated geoelectrical and seismic methods: A case study in Thungsong site, southern Thailand.

Journal: Heliyon
Published: June 21, 2023

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.

Journal: bioRxiv : the preprint server for biology
Published: March 30, 2023

Macromolecular condensation buffers intracellular water potential.

Macromolecular condensation buffers intracellular water potential.

Journal: Nature
Published: November 17, 2022
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Last Updated: 09/26/2026