Joseph L. Janssen

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 58 publications

Hypothesis: Nutrient Off-Loading and Ectopic Fat Reduction Reverse Insulin Resistance and Improve Cardiovascular Outcomes in Type 2 Diabetes-A Narrative Review.

Hypothesis: Nutrient Off-Loading and Ectopic Fat Reduction Reverse Insulin Resistance and Improve Cardiovascular Outcomes in Type 2 Diabetes-A Narrative Review.

Journal: International journal of molecular sciences

Published: December 14, 2025

The Pivotal Role of the Western Diet, Hyperinsulinemia, Ectopic Fat, and Diacylglycerol-Mediated Insulin Resistance in Type 2 Diabetes.

The Pivotal Role of the Western Diet, Hyperinsulinemia, Ectopic Fat, and Diacylglycerol-Mediated Insulin Resistance in Type 2 Diabetes.

Journal: International journal of molecular sciences

Published: July 04, 2025

G Protein-coupled and Membrane Tyrosine Kinase Receptor Relationships Yield Therapeutic Opportunities.

G Protein-coupled and Membrane Tyrosine Kinase Receptor Relationships Yield Therapeutic Opportunities.

Journal: Endocrine reviews

Published: December 03, 2024

The Causal Role of Ectopic Fat Deposition in the Pathogenesis of Metabolic Syndrome.

The Causal Role of Ectopic Fat Deposition in the Pathogenesis of Metabolic Syndrome.

Journal: International journal of molecular sciences

Published: November 05, 2024

Ultra-processed foods and type 2 diabetes: more fundamental research is needed.

Ultra-processed foods and type 2 diabetes: more fundamental research is needed.

Journal: The Lancet regional health. Europe

Published: September 10, 2024

Overnutrition, Hyperinsulinemia and Ectopic Fat: It Is Time for A Paradigm Shift in the Management of Type 2 Diabetes.

Overnutrition, Hyperinsulinemia and Ectopic Fat: It Is Time for A Paradigm Shift in the Management of Type 2 Diabetes.

Journal: International journal of molecular sciences

Published: April 15, 2024

The Impact of Westernization on the Insulin/IGF-I Signaling Pathway and the Metabolic Syndrome: It Is Time for Change.

The Impact of Westernization on the Insulin/IGF-I Signaling Pathway and the Metabolic Syndrome: It Is Time for Change.

Journal: International journal of molecular sciences

Published: January 27, 2023

New Insights into the Role of Insulin and Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Metabolic Syndrome.

New Insights into the Role of Insulin and Hypothalamic-Pituitary-Adrenal (HPA) Axis in the Metabolic Syndrome.

Journal: International journal of molecular sciences

Published: June 22, 2022

It Takes Two to Tango: IGF-I and TSH Receptors in Thyroid Eye Disease.

It Takes Two to Tango: IGF-I and TSH Receptors in Thyroid Eye Disease.

Journal: The Journal of clinical endocrinology and metabolism

Published: December 15, 2021

Hyperinsulinemia and Its Pivotal Role in Aging, Obesity, Type 2 Diabetes, Cardiovascular Disease and Cancer.

Hyperinsulinemia and Its Pivotal Role in Aging, Obesity, Type 2 Diabetes, Cardiovascular Disease and Cancer.

Journal: International journal of molecular sciences

Published: June 16, 2021

Lessons Learned from Targeting IGF-I Receptor in Thyroid-Associated Ophthalmopathy.

Lessons Learned from Targeting IGF-I Receptor in Thyroid-Associated Ophthalmopathy.

Journal: Cells

Published: January 24, 2021

Modifying Effects of Glucose and Insulin/Insulin-Like Growth Factors on Colon Cancer Cells.

Modifying Effects of Glucose and Insulin/Insulin-Like Growth Factors on Colon Cancer Cells.

Journal: Frontiers in oncology

Published: December 23, 2020

Showing 1-12 of 58

Last Updated: 09/26/2026