Joseph Saad

Helsinki, Finland

Last Updated: 09/26/2026

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Found 11 publications

NAMPT haploinsufficiency is a therapeutic vulnerability to NAMPT inhibition in -7/-7q MDS.

NAMPT haploinsufficiency is a therapeutic vulnerability to NAMPT inhibition in -7/-7q MDS.

Journal: Biomarker research
Published: March 25, 2026

Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy.

Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy.

Journal: HemaSphere
Published: June 24, 2025

Predictors of response and rational combinations for the novel MCL-1 inhibitor MIK665 in acute myeloid leukemia.

Predictors of response and rational combinations for the novel MCL-1 inhibitor MIK665 in acute myeloid leukemia.

Journal: Molecular oncology
Published: February 06, 2025

DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes.

DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes.

Journal: Leukemia
Published: October 15, 2024

Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial.

Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial.

Journal: Blood
Published: April 11, 2024

Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia.

Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia.

Journal: Blood advances
Published: April 11, 2023

Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.

Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.

Journal: Blood advances
Published: May 06, 2022

Megakaryopoiesis impairment through acute innate immune signaling activation by azacitidine.

Megakaryopoiesis impairment through acute innate immune signaling activation by azacitidine.

Journal: The Journal of experimental medicine
Published: November 01, 2021

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia.

Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia.

Journal: Blood
Published: February 01, 2021

DrugComb: an integrative cancer drug combination data portal.

DrugComb: an integrative cancer drug combination data portal.

Journal: Nucleic acids research
Published: February 24, 2019

Making Sense of the Epigenome Using Data Integration Approaches.

Making Sense of the Epigenome Using Data Integration Approaches.

Journal: Frontiers in pharmacology
Published: November 22, 2018
Showing 1-11 of 11

Last Updated: 09/26/2026