Joshua I. Siner

Hematology
4921 Parkview Pl Ste 7B
Saint Louis, MO 63110

Last Updated: 09/26/2026

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Found 6 publications

Roles of megakaryocytes and platelets in myeloproliferative neoplasms.

Roles of megakaryocytes and platelets in myeloproliferative neoplasms.

Journal: Current opinion in hematology
Published: June 17, 2026

Galectin-1 Fuels Monocyte Hyperinflammation and Represents a Novel Therapeutic Target in Myeloproliferative Neoplasms.

Galectin-1 Fuels Monocyte Hyperinflammation and Represents a Novel Therapeutic Target in Myeloproliferative Neoplasms.

Journal: Blood
Published: December 05, 2025

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.

Journal: JCI insight
Published: October 14, 2016

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A.

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A.

Journal: Journal of thrombosis and haemostasis : JTH
Published: July 12, 2016

AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.

AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.

Journal: Blood
Published: January 09, 2015

Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype.

Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype.

Journal: Blood
Published: February 02, 2013
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Last Updated: 09/26/2026