Juan Dubrot

Geneve, GE, Switzerland

Last Updated: 09/26/2026

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Found 34 publications

Radiotherapy and AAV-based immunotherapy: A new alliance for cancer treatment.

Radiotherapy and AAV-based immunotherapy: A new alliance for cancer treatment.

Journal: Molecular therapy. Oncology

Published: July 13, 2026

Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors.

Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors.

Journal: bioRxiv : the preprint server for biology

Published: June 29, 2026

Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity.

Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity.

Journal: Cancer cell

Published: December 17, 2024

In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target.

In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target.

Journal: Nature communications

Published: December 07, 2024

Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications.

Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications.

Journal: Seminars in cancer biology

Published: October 01, 2024

Inflammatory cytokines induce new cancer dependencies.

Inflammatory cytokines induce new cancer dependencies.

Journal: Nature genetics

Published: July 27, 2024

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint.

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint.

Journal: Immunity

Published: January 18, 2024

Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.

Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.

Journal: Nature communications

Published: September 26, 2023

Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors.

Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors.

Journal: STAR protocols

Published: October 27, 2022

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer.

Journal: Nature immunology

Published: January 04, 2022

Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.

Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.

Journal: Cancer discovery

Published: August 10, 2021

MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell-Suppressive Functions.

MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell-Suppressive Functions.

Journal: Cancer immunology research

Published: September 16, 2020

Showing 1-12 of 34

Last Updated: 09/26/2026