Juan J. Espinosa-Ramirez

Juarez, CHH 32310, Mexico

Last Updated: 09/26/2026

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Found 13 publications

Synthesis, in vitro, in silico and in vivo hypoglycemic and lipid-lowering effects of 4-benzyloxy-5-benzylidene-1,3-thiazolidine-2,4-diones mediated by dual PPAR α/γ modulation.

Synthesis, in vitro, in silico and in vivo hypoglycemic and lipid-lowering effects of 4-benzyloxy-5-benzylidene-1,3-thiazolidine-2,4-diones mediated by dual PPAR α/γ modulation.

Journal: Bioorganic & medicinal chemistry letters

Published: April 11, 2022

Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study.

Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 13, 2018

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice.

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice.

Journal: Molecules (Basel, Switzerland)

Published: November 24, 2017

Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.

Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.

Journal: Drug development research

Published: November 14, 2017

Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.

Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.

Journal: Bioorganic & medicinal chemistry

Published: February 09, 2016

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives.

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives.

Journal: Bioorganic & medicinal chemistry letters

Published: January 06, 2016

1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies.

1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies.

Journal: European journal of medicinal chemistry

Published: February 23, 2015

Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect.

Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect.

Journal: Bioorganic & medicinal chemistry letters

Published: June 19, 2014

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.

Journal: European journal of medicinal chemistry

Published: June 09, 2014

Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.

Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.

Journal: European journal of medicinal chemistry

Published: June 27, 2013

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model.

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model.

Journal: European journal of medicinal chemistry

Published: June 04, 2013

Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual PPAR α/γ modulator with antidiabetic effect: in vitro, in silico and in vivo approaches.

Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual PPAR α/γ modulator with antidiabetic effect: in vitro, in silico and in vivo approaches.

Journal: Chemical biology & drug design

Published: November 08, 2012

Showing 1-12 of 13

Last Updated: 09/26/2026