Julia Harwardt

Darmstadt, HE, Germany

Last Updated: 09/26/2026

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Found 17 publications

Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics.

Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics.

Journal: mAbs
Published: September 02, 2026

Fc-Silenced CD89 × EGFR Bispecific Antibodies Promote Neutrophil and Macrophage Antitumor Activity.

Fc-Silenced CD89 × EGFR Bispecific Antibodies Promote Neutrophil and Macrophage Antitumor Activity.

Journal: Antibodies (Basel, Switzerland)
Published: May 22, 2026

Protocol for in vitro profiling of key TNF downstream signaling pathways involved in cell death and pro-survival signaling in cancer cells.

Protocol for in vitro profiling of key TNF downstream signaling pathways involved in cell death and pro-survival signaling in cancer cells.

Journal: STAR protocols
Published: April 21, 2026

Antigen-directed single domain antibody-based TNFR1 agonists elicit preferential killing of HER2-overexpressing cancer cells.

Antigen-directed single domain antibody-based TNFR1 agonists elicit preferential killing of HER2-overexpressing cancer cells.

Journal: iScience
Published: October 16, 2025

Optimizing colloidal stability and viscosity of multispecific antibodies at the drug discovery-development interface: a systematic predictive case study.

Optimizing colloidal stability and viscosity of multispecific antibodies at the drug discovery-development interface: a systematic predictive case study.

Journal: mAbs
Published: September 01, 2025

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities.

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities.

Journal: Protein science : a publication of the Protein Society
Published: October 22, 2024

On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.

On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.

Journal: Protein science : a publication of the Protein Society
Published: July 04, 2024

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies.

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies.

Journal: Frontiers in immunology
Published: July 01, 2024

T cell receptor-directed antibody-drug conjugates for the treatment of T cell-derived cancers.

T cell receptor-directed antibody-drug conjugates for the treatment of T cell-derived cancers.

Journal: Molecular therapy. Oncology
Published: March 30, 2024

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1.

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1.

Journal: Antibodies (Basel, Switzerland)
Published: February 09, 2024

Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager.

Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager.

Journal: Molecules (Basel, Switzerland)
Published: November 30, 2023

Better safe than sorry: dual targeting antibodies for cancer immunotherapy.

Better safe than sorry: dual targeting antibodies for cancer immunotherapy.

Journal: Biological chemistry
Published: October 17, 2023
Showing 1-12 of 17

Last Updated: 09/26/2026