Julie Dumont

Lille, France

Last Updated: 09/26/2026

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Found 32 publications

Non-microglial downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease-related hallmarks.

Non-microglial downregulation of PLCG2 impairs synaptic function and elicits Alzheimer disease-related hallmarks.

Journal: bioRxiv : the preprint server for biology
Published: April 03, 2026

Discovery of pyrimidine-based small activators of insulin degrading enzyme.

Discovery of pyrimidine-based small activators of insulin degrading enzyme.

Journal: European journal of medicinal chemistry
Published: June 10, 2025

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin-degrading enzyme, a new molecular vulnerability in multiple myeloma.

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin-degrading enzyme, a new molecular vulnerability in multiple myeloma.

Journal: British journal of pharmacology
Published: October 14, 2024

Calpain and caspase regulate Aβ peptide production via cleavage of KINDLIN2 encoded by the AD-associated gene FERMT2.

Calpain and caspase regulate Aβ peptide production via cleavage of KINDLIN2 encoded by the AD-associated gene FERMT2.

Journal: Neurobiology of aging
Published: July 04, 2024

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Journal: Nature genetics
Published: May 17, 2024

Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach.

Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach.

Journal: Communications biology
Published: February 06, 2024

High-Content Screening of Synaptic Density Modulators in Primary Neuronal Cultures.

High-Content Screening of Synaptic Density Modulators in Primary Neuronal Cultures.

Journal: Current protocols
Published: October 26, 2023

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.

Journal: Journal of medicinal chemistry
Published: August 28, 2023

Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.

Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.

Journal: EMBO molecular medicine
Published: July 03, 2023

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.

Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.

Journal: European journal of medicinal chemistry
Published: December 05, 2022

Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.

Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis.

Journal: Angewandte Chemie (International ed. in English)
Published: March 08, 2022

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.

Journal: PLoS pathogens
Published: November 19, 2021
Showing 1-12 of 32

Last Updated: 09/26/2026