Julien Dairou

Paris, 75013, France

Last Updated: 09/26/2026

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Found 91 publications

Enhancing virtual screening of cystathionine β-synthase inhibitors: benchmarking target-specific machine-learning scoring functions against state-of-the-art AI docking and co-folding approaches.

Enhancing virtual screening of cystathionine β-synthase inhibitors: benchmarking target-specific machine-learning scoring functions against state-of-the-art AI docking and co-folding approaches.

Journal: Journal of cheminformatics
Published: March 09, 2026

Erlotinib and Leflunomide Disrupt 6-Formylindolo[3,2-b]Carbazole Metabolism and Sensitize Keratinocytes to UVA Radiation-Induced Apoptosis.

Erlotinib and Leflunomide Disrupt 6-Formylindolo[3,2-b]Carbazole Metabolism and Sensitize Keratinocytes to UVA Radiation-Induced Apoptosis.

Journal: Photodermatology, photoimmunology & photomedicine
Published: February 26, 2026

Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 iPSC-derived neural cells.

Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 iPSC-derived neural cells.

Journal: bioRxiv : the preprint server for biology
Published: February 12, 2026

Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography.

Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography.

Journal: ACS pharmacology & translational science
Published: February 04, 2026

Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 induced pluripotent stem cell-derived neural cells.

Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 induced pluripotent stem cell-derived neural cells.

Journal: Disease models & mechanisms
Published: November 04, 2025

Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays.

Chemical fate in vitro: A physiological biokinetic (PBK) model for cell-based assays.

Journal: ALTEX
Published: September 26, 2025

DYRK1A inhibition restores pancreatic functions and improves glucose metabolism in a preclinical model of type 2 diabetes.

DYRK1A inhibition restores pancreatic functions and improves glucose metabolism in a preclinical model of type 2 diabetes.

Journal: Molecular metabolism
Published: August 04, 2025

Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase.

Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase.

Journal: The Journal of biological chemistry
Published: May 07, 2025

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography.

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography.

Journal: Biochimie
Published: April 16, 2025

An immunoprecipitation-based assay to assess cysteine-106-dependent catalytic activity of human-protein DJ-1 in cell line lysates.

An immunoprecipitation-based assay to assess cysteine-106-dependent catalytic activity of human-protein DJ-1 in cell line lysates.

Journal: Analytical biochemistry
Published: April 03, 2025

Inhibition of the Parkinson's Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family.

Inhibition of the Parkinson's Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family.

Journal: ACS chemical neuroscience
Published: February 26, 2025

Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes.

Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes.

Journal: Molecular pharmacology
Published: December 16, 2024
Showing 1-12 of 91

Last Updated: 09/26/2026