Julien Lancelot
Lille, 59000, France
Last Updated: 09/26/2026
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Found 23 publications
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Journal: European journal of medicinal chemistry
Published: June 17, 2021
Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni.
Journal: PLoS neglected tropical diseases
Published: May 21, 2021
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.
Journal: PLoS neglected tropical diseases
Published: November 08, 2019
Structure-Based Design, Synthesis, and Biological Evaluation of Triazole-Based smHDAC8 Inhibitors.
Journal: ChemMedChem
Published: October 18, 2019
Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2).
Journal: Journal of medicinal chemistry
Published: September 10, 2019
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Journal: Journal of medicinal chemistry
Published: October 23, 2018
Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.
Journal: ChemMedChem
Published: April 11, 2018
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing.
Journal: Molecules (Basel, Switzerland)
Published: January 30, 2018
Analysis of the interactome of Schistosoma mansoni histone deacetylase 8.
Journal: PLoS neglected tropical diseases
Published: June 13, 2017
Isophthalic Acid-Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni.
Journal: Archiv der Pharmazie
Published: March 16, 2017
Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.
Journal: International journal for parasitology. Drugs and drug resistance
Published: October 29, 2016
Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis.
Journal: Journal of medicinal chemistry
Published: March 04, 2016
Last Updated: 09/26/2026