Jun-ichi Takeshita

Shizuoka, Japan

Last Updated: 09/26/2026

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Found 35 publications

Ordinal association between cytochrome P450 inhibition and hepatotoxicity severity in rats.

Ordinal association between cytochrome P450 inhibition and hepatotoxicity severity in rats.

Journal: The Journal of toxicological sciences

Published: May 06, 2026

Pulmonary responses to polyacrylic acid with and without carboxyl groups following intratracheal instillation in rats.

Pulmonary responses to polyacrylic acid with and without carboxyl groups following intratracheal instillation in rats.

Journal: Archives of toxicology

Published: November 27, 2025

Polyacrylic acid, but not polyethylene glycol, induces metabolic reprogramming linked to pulmonary fibrosis in rats.

Polyacrylic acid, but not polyethylene glycol, induces metabolic reprogramming linked to pulmonary fibrosis in rats.

Journal: Scientific reports

Published: October 07, 2025

Characterization of the toxicological findings from 90-day and 2-year repeated-dose toxicity studies of pesticides in rats.

Characterization of the toxicological findings from 90-day and 2-year repeated-dose toxicity studies of pesticides in rats.

Journal: The Journal of toxicological sciences

Published: October 01, 2025

Development of a new alternative method to inhalation exposure: intratracheal instillation studies using molecular dispersion.

Development of a new alternative method to inhalation exposure: intratracheal instillation studies using molecular dispersion.

Journal: Environmental health and preventive medicine

Published: September 10, 2025

Read-across prediction of nongenotoxic thyroid carcinogenicity of pesticides in rats using mechanism-based in vitro assay data.

Read-across prediction of nongenotoxic thyroid carcinogenicity of pesticides in rats using mechanism-based in vitro assay data.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: September 05, 2025

Mechanism-based prediction of drug synergy via network controllability analysis of therapeutic pathways in intractable diseases.

Mechanism-based prediction of drug synergy via network controllability analysis of therapeutic pathways in intractable diseases.

Journal: iScience

Published: August 01, 2025

Utility of in vitro assay data in read-across prediction of nongenotoxic carcinogenicity of pesticides for cytotoxicity-related rat tumors.

Utility of in vitro assay data in read-across prediction of nongenotoxic carcinogenicity of pesticides for cytotoxicity-related rat tumors.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: February 22, 2025

Comprehensive analysis of the toxicity-related findings from repeated-dose subacute toxicity studies of industrial chemicals in male rats.

Comprehensive analysis of the toxicity-related findings from repeated-dose subacute toxicity studies of industrial chemicals in male rats.

Journal: Critical reviews in toxicology

Published: December 05, 2024

Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates.

Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: November 18, 2024

Inhalation exposure to cross-linked polyacrylic acid induces pulmonary disorders.

Inhalation exposure to cross-linked polyacrylic acid induces pulmonary disorders.

Journal: Toxicology

Published: September 19, 2024

The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs.

The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs.

Journal: Scientific reports

Published: July 08, 2024

Showing 1-12 of 35

Last Updated: 09/26/2026