Jung-ae Kim

Gyeongsan-si, Republic of Korea

Last Updated: 09/26/2026

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Found 129 publications

Discovery and Pharmacological Characterization of a Dual-Acting 2-Amino-3-Cyanopyridine Inhibitor Targeting Microtubule Polymerization and GAK.

Discovery and Pharmacological Characterization of a Dual-Acting 2-Amino-3-Cyanopyridine Inhibitor Targeting Microtubule Polymerization and GAK.

Journal: Journal of medicinal chemistry

Published: June 16, 2026

Design, synthesis, and biological evaluation of clovamide analogues as anti-colitis agents modulating NF-κB/STAT3/iNOS signaling.

Design, synthesis, and biological evaluation of clovamide analogues as anti-colitis agents modulating NF-κB/STAT3/iNOS signaling.

Journal: Bioorganic chemistry

Published: April 15, 2026

Molecular epidemiology and outcomes of EGFR exon 20 insertion in Korean patients with non-small cell lung cancer.

Molecular epidemiology and outcomes of EGFR exon 20 insertion in Korean patients with non-small cell lung cancer.

Journal: Translational lung cancer research

Published: November 30, 2025

Aβ₁₋₄₀ Enhances Platelet Sensitivity to Thrombin via NADPH Oxidase-ROS Signaling and Integrin αIIbβ₃ Engagement.

Aβ₁₋₄₀ Enhances Platelet Sensitivity to Thrombin via NADPH Oxidase-ROS Signaling and Integrin αIIbβ₃ Engagement.

Journal: Biomolecules & therapeutics

Published: November 05, 2025

Inhibition of nuclear ROCK2 by a novel thiourea derivative induces potent antitumor effects through PTEN/FOXO1 pathway restoration in prostate cancer.

Inhibition of nuclear ROCK2 by a novel thiourea derivative induces potent antitumor effects through PTEN/FOXO1 pathway restoration in prostate cancer.

Journal: Bioorganic chemistry

Published: August 18, 2025

Therapeutic targeting of GSK-3β activation by the tyrosine kinase RYK in pancreatic ductal adenocarcinoma with BJ-2412, a novel sunitinib analogue.

Therapeutic targeting of GSK-3β activation by the tyrosine kinase RYK in pancreatic ductal adenocarcinoma with BJ-2412, a novel sunitinib analogue.

Journal: British journal of pharmacology

Published: June 23, 2025

Development of 9-cinnamyl-9H-purine derivatives as potent anticancer agents through inactivation of NF-κb/p65 and p-STAT1 signaling pathways: Discovery of a new template for adenosine receptor.

Development of 9-cinnamyl-9H-purine derivatives as potent anticancer agents through inactivation of NF-κb/p65 and p-STAT1 signaling pathways: Discovery of a new template for adenosine receptor.

Journal: Bioorganic chemistry

Published: February 04, 2025

Discovery of a novel molecular glue degrader targeting GSPT1/2 with a non-IMiD-based CRBN binder.

Discovery of a novel molecular glue degrader targeting GSPT1/2 with a non-IMiD-based CRBN binder.

Journal: European journal of medicinal chemistry

Published: January 14, 2025

International comparison of generic competition, prices, and usage trends: South Korea and G20 countries.

International comparison of generic competition, prices, and usage trends: South Korea and G20 countries.

Journal: Frontiers in public health

Published: January 13, 2025

Discovery of novel WRN inhibitors for treating MSI-H colorectal cancers.

Discovery of novel WRN inhibitors for treating MSI-H colorectal cancers.

Journal: Bioorganic & medicinal chemistry letters

Published: January 06, 2025

Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming.

Prostate cancer-selective anticancer action of an oxindole derivative via HO-1-mediated disruption of metabolic reprogramming.

Journal: Chemico-biological interactions

Published: November 13, 2024

Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle.

Design and evaluation of anaplastic lymphoma kinase degraders using a covalent fumarate handle.

Journal: Bioorganic & medicinal chemistry letters

Published: August 21, 2024

Showing 1-12 of 129

Last Updated: 09/26/2026