Junqiu W. Xie

Key Laboratory Of Preclinical Study For New Drugs Of Gansu Province, 2019RU066
Lanzhou, 730000, China

Last Updated: 09/26/2026

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Found 55 publications

All-Hydrocarbon Stapling and Amino Acid Substitution-Modified Antimicrobial Peptide Feleucin-K3 Analogs Enhanced the Stability and Optimized the Therapeutic Index against Multidrug-Resistant Bacteria.

All-Hydrocarbon Stapling and Amino Acid Substitution-Modified Antimicrobial Peptide Feleucin-K3 Analogs Enhanced the Stability and Optimized the Therapeutic Index against Multidrug-Resistant Bacteria.

Journal: Journal of medicinal chemistry

Published: June 09, 2026

Postmodification of Daptomycin at Tryptophan Enables the Discovery of Aryl-Daptomycin Antibiofilm Activity against MRSA.

Postmodification of Daptomycin at Tryptophan Enables the Discovery of Aryl-Daptomycin Antibiofilm Activity against MRSA.

Journal: Journal of medicinal chemistry

Published: May 26, 2026

Cyclization-Based Optimization of the Antimicrobial Peptide YD Yields a Nanomolar Inhibitor of Pulmonary Fibrosis.

Cyclization-Based Optimization of the Antimicrobial Peptide YD Yields a Nanomolar Inhibitor of Pulmonary Fibrosis.

Journal: Journal of medicinal chemistry

Published: March 13, 2026

Halogenated Sulfono-γ-AApeptides Modified Cationic AMPs Have Enhanced Stability and Therapeutic Potential against Clinically Important MDR Infections.

Halogenated Sulfono-γ-AApeptides Modified Cationic AMPs Have Enhanced Stability and Therapeutic Potential against Clinically Important MDR Infections.

Journal: ACS infectious diseases

Published: June 12, 2025

Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria.

Rational two-round modification for developing isopeptide bond-containing antimicrobial peptide with enhanced stability and potent activity against multidrug-resistant gram-negative bacteria.

Journal: Biochemical pharmacology

Published: June 04, 2025

Iterative Optimization Yields Stapled Peptides with Superior Pharmacokinetics and Potency for Renal Fibrosis Treatment.

Iterative Optimization Yields Stapled Peptides with Superior Pharmacokinetics and Potency for Renal Fibrosis Treatment.

Journal: Journal of medicinal chemistry

Published: April 08, 2025

Naturally inspired chimeric quinolone derivatives to reverse bacterial drug resistance.

Naturally inspired chimeric quinolone derivatives to reverse bacterial drug resistance.

Journal: European journal of medicinal chemistry

Published: February 06, 2025

Michael Addition Reaction between Dehydroalanines and Phosphites Enabled the Introduction of Phosphonates into Oligopeptides.

Michael Addition Reaction between Dehydroalanines and Phosphites Enabled the Introduction of Phosphonates into Oligopeptides.

Journal: Organic letters

Published: May 23, 2024

Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy.

Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy.

Journal: Biochemical pharmacology

Published: January 24, 2024

Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis.

Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis.

Journal: ACS pharmacology & translational science

Published: January 11, 2024

Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts.

Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts.

Journal: Nature communications

Published: December 08, 2023

Visible-Light Mediated Deoxygenation of Carboxylic Acid for Late-Stage Peptide Modification Targeting Dehydroalanine.

Visible-Light Mediated Deoxygenation of Carboxylic Acid for Late-Stage Peptide Modification Targeting Dehydroalanine.

Journal: Organic letters

Published: November 15, 2023

Showing 1-12 of 55

Last Updated: 09/26/2026