Justin R. Harrison

Dow Street
Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.

Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.

Journal: ACS infectious diseases

Published: February 27, 2025

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Journal: Journal of medicinal chemistry

Published: March 18, 2022

An Evaluation of Wound Healing Efficacy of a Film Dressing Made from Polymer-integrated Amnion Membrane.

An Evaluation of Wound Healing Efficacy of a Film Dressing Made from Polymer-integrated Amnion Membrane.

Journal: Organogenesis

Published: November 09, 2020

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease.

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease.

Journal: Journal of medicinal chemistry

Published: March 06, 2020

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis.

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis.

Journal: Science (New York, N.Y.)

Published: October 09, 2018

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.

Journal: Journal of medicinal chemistry

Published: September 13, 2018

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

Journal: ACS infectious diseases

Published: March 10, 2018

Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.

Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.

Journal: PLoS neglected tropical diseases

Published: November 18, 2015

N-myristoyltransferase is a cell wall target in Aspergillus fumigatus.

N-myristoyltransferase is a cell wall target in Aspergillus fumigatus.

Journal: ACS chemical biology

Published: February 24, 2015

Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.

Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.

Journal: Journal of medicinal chemistry

Published: November 21, 2014

A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei.

A novel allosteric inhibitor of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei.

Journal: ACS chemical biology

Published: July 10, 2013

Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

Journal: Journal of medicinal chemistry

Published: December 14, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026