Kadri Seppa

Tartu, Estonia

Last Updated: 09/26/2026

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Found 11 publications

Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome.

Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome.

Journal: Frontiers in endocrinology
Published: June 05, 2023

Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome.

Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome.

Journal: Genes
Published: November 28, 2022

Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala.

Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala.

Journal: Frontiers in immunology
Published: July 27, 2022

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype.

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype.

Journal: Cells
Published: October 06, 2021

The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome.

The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome.

Journal: Genes
Published: September 16, 2021

Alternative Promoter Use Governs the Expression of IgLON Cell Adhesion Molecules in Histogenetic Fields of the Embryonic Mouse Brain.

Alternative Promoter Use Governs the Expression of IgLON Cell Adhesion Molecules in Histogenetic Fields of the Embryonic Mouse Brain.

Journal: International journal of molecular sciences
Published: May 10, 2021

Age- and airway disease related gene expression patterns of key SARS-CoV-2 entry factors in human nasal epithelia.

Age- and airway disease related gene expression patterns of key SARS-CoV-2 entry factors in human nasal epithelia.

Journal: Virology
Published: January 21, 2021

Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model.

Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model.

Journal: Scientific reports
Published: October 26, 2020

GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome.

GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome.

Journal: Scientific reports
Published: May 13, 2019

Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome.

Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome.

Journal: Scientific reports
Published: February 15, 2018

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration.

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration.

Journal: Scientific reports
Published: March 14, 2017
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Last Updated: 09/26/2026