Kam Y. Zhang

Pl 64
Helsinki, 00014, Finland

Last Updated: 09/26/2026

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Found 116 publications

Discovery of novel 4-aminobenzamide derivatives as small molecule CBX2 inhibitors.

Discovery of novel 4-aminobenzamide derivatives as small molecule CBX2 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: October 31, 2025

The Ser7 phosphorylation of RNA polymerase II-CTD is required for the recruitment of E3 ubiquitin ligase Asr1 and subtelomeric gene silencing.

The Ser7 phosphorylation of RNA polymerase II-CTD is required for the recruitment of E3 ubiquitin ligase Asr1 and subtelomeric gene silencing.

Journal: The Journal of biological chemistry

Published: May 06, 2025

Identification of substituted acetanilide compounds as small molecule CBX2 inhibitors via in silico screening.

Identification of substituted acetanilide compounds as small molecule CBX2 inhibitors via in silico screening.

Journal: Biochemical and biophysical research communications

Published: April 16, 2025

Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice.

Phosphorylation of Runx protein controls helper CD4+ T cell versus cytotoxic CD8+ T cell lineage choice.

Journal: Nature immunology

Published: February 02, 2025

Expression, Purification, and Preliminary Characterization of Putative Protein Tyrosine Phosphatase Oca1.

Expression, Purification, and Preliminary Characterization of Putative Protein Tyrosine Phosphatase Oca1.

Journal: Protein and peptide letters

Published: January 25, 2025

Discovery of a Compound That Inhibits IRE1α S-Nitrosylation and Preserves the Endoplasmic Reticulum Stress Response under Nitrosative Stress.

Discovery of a Compound That Inhibits IRE1α S-Nitrosylation and Preserves the Endoplasmic Reticulum Stress Response under Nitrosative Stress.

Journal: ACS chemical biology

Published: November 12, 2024

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein.

Journal: Journal of chemical information and modeling

Published: November 05, 2024

Identification of benzimidazole-6-carboxamide based inhibitors of secretory glutaminyl cyclase for the treatment of Alzheimer's disease.

Identification of benzimidazole-6-carboxamide based inhibitors of secretory glutaminyl cyclase for the treatment of Alzheimer's disease.

Journal: International journal of biological macromolecules

Published: August 09, 2024

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.

RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.

Journal: The Journal of biological chemistry

Published: December 28, 2023

A community effort in SARS-CoV-2 drug discovery.

A community effort in SARS-CoV-2 drug discovery.

Journal: Molecular informatics

Published: September 29, 2023

The Ser7 of RNA Pol II-CTD influences the recruitment of Cdc73 for mRNA transcription.

The Ser7 of RNA Pol II-CTD influences the recruitment of Cdc73 for mRNA transcription.

Journal: International journal of biological macromolecules

Published: September 21, 2023

The Saccharomyces cerevisiae SR protein Npl3 interacts with hyperphosphorylated CTD of RNA Polymerase II.

The Saccharomyces cerevisiae SR protein Npl3 interacts with hyperphosphorylated CTD of RNA Polymerase II.

Journal: International journal of biological macromolecules

Published: July 26, 2023

Showing 1-12 of 116

Last Updated: 09/26/2026