Kamil Paruch

St. Anne's University Hospital
Brno, JM 65691, Czech Republic

Last Updated: 09/26/2026

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Found 35 publications

Discovery of Two Structurally Distinct Classes of Inhibitors Targeting the Nuclease MUS81 and Enhancing Efficacy of Chemotherapy in Cancer Cells.

Discovery of Two Structurally Distinct Classes of Inhibitors Targeting the Nuclease MUS81 and Enhancing Efficacy of Chemotherapy in Cancer Cells.

Journal: Journal of medicinal chemistry

Published: February 25, 2026

CDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing.

CDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing.

Journal: Nucleic acids research

Published: March 30, 2025

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.

Journal: Journal of medicinal chemistry

Published: July 18, 2024

Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode.

Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode.

Journal: Angewandte Chemie (International ed. in English)

Published: July 08, 2024

Discovery of new inhibitors of nuclease MRE11.

Discovery of new inhibitors of nuclease MRE11.

Journal: European journal of medicinal chemistry

Published: May 28, 2024

Unexpectedly Regioselective Diels-Alder Reactions of New Unsymmetrical Benzoquinones: A Convenient Synthetic Entry to Uniquely Substituted Decalins.

Unexpectedly Regioselective Diels-Alder Reactions of New Unsymmetrical Benzoquinones: A Convenient Synthetic Entry to Uniquely Substituted Decalins.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: March 15, 2024

Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells.

Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells.

Journal: Biological chemistry

Published: January 13, 2023

Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.

Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.

Journal: Nature communications

Published: January 10, 2023

Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.

Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.

Journal: Angewandte Chemie (International ed. in English)

Published: November 28, 2022

Geometric Control of Cell Behavior by Biomolecule Nanodistribution.

Geometric Control of Cell Behavior by Biomolecule Nanodistribution.

Journal: ACS biomaterials science & engineering

Published: October 06, 2022

Comparing the efficiency of six clearing methods in developing seeds of Arabidopsis thaliana.

Comparing the efficiency of six clearing methods in developing seeds of Arabidopsis thaliana.

Journal: Plant reproduction

Published: September 12, 2022

Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules.

Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules.

Journal: Angewandte Chemie (International ed. in English)

Published: September 06, 2022

Showing 1-12 of 35

Last Updated: 09/26/2026