Kan Yang

Key Laboratory Of Pharmaceutical Quality Control Of Hebei Province
Baoding, 071002, China

Last Updated: 09/26/2026

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Found 32 publications

Discovery of 1,3-disubstituted indole derivatives as ATP-competitive inhibitors of sphingosine kinase for tumor therapy.

Discovery of 1,3-disubstituted indole derivatives as ATP-competitive inhibitors of sphingosine kinase for tumor therapy.

Journal: European journal of medicinal chemistry

Published: March 19, 2026

Targeting S1P signaling for drug development.

Targeting S1P signaling for drug development.

Journal: Drug discovery today

Published: December 14, 2025

N-myristoyltransferases: structure, function, disease, and inhibitors.

N-myristoyltransferases: structure, function, disease, and inhibitors.

Journal: Drug discovery today

Published: December 12, 2025

An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.

An Enhanced Cancer Immunogenic Cell Death Strategy: Fibrate-Oxaliplatin(IV) Conjugates with Modulating Tumor Immune Microenvironment.

Journal: Journal of medicinal chemistry

Published: December 09, 2025

Unveiling Unusual Reactivity of SO2 and Unusual Type of S-X Long Bonds.

Unveiling Unusual Reactivity of SO2 and Unusual Type of S-X Long Bonds.

Journal: Inorganic chemistry

Published: July 08, 2025

Design, Synthesis, and Bioactivity Evaluation of a Palmitoyltransferase Inhibitor Based on the PAP Structure.

Design, Synthesis, and Bioactivity Evaluation of a Palmitoyltransferase Inhibitor Based on the PAP Structure.

Journal: Chemistry & biodiversity

Published: April 17, 2025

Modulating culture method promotes the production of disulfide-linked resorcylic acid lactone dimers with anti-proliferative activity.

Modulating culture method promotes the production of disulfide-linked resorcylic acid lactone dimers with anti-proliferative activity.

Journal: Bioorganic chemistry

Published: February 13, 2025

Insights into direct KRAS inhibition strategies for cancer treatment.

Insights into direct KRAS inhibition strategies for cancer treatment.

Journal: Future medicinal chemistry

Published: November 21, 2024

Regulation of post-translational modification of PD-L1 and associated opportunities for novel small-molecule therapeutics.

Regulation of post-translational modification of PD-L1 and associated opportunities for novel small-molecule therapeutics.

Journal: Future medicinal chemistry

Published: July 01, 2024

Discovery of a Novel ASM Direct Inhibitor with a 1,5-Diphenyl-pyrazole Scaffold and Its Antidepressant Mechanism of Action.

Discovery of a Novel ASM Direct Inhibitor with a 1,5-Diphenyl-pyrazole Scaffold and Its Antidepressant Mechanism of Action.

Journal: Journal of medicinal chemistry

Published: June 18, 2024

Discovery and biological evaluation of biaryl acetamide derivatives as selective and in vivo active sphingosine kinase-2 inhibitors.

Discovery and biological evaluation of biaryl acetamide derivatives as selective and in vivo active sphingosine kinase-2 inhibitors.

Journal: European journal of medicinal chemistry

Published: April 12, 2024

Modulators for palmitoylation of proteins and small molecules.

Modulators for palmitoylation of proteins and small molecules.

Journal: European journal of medicinal chemistry

Published: February 09, 2024

Showing 1-12 of 32

Last Updated: 09/26/2026