Kanako Tachikawa

Izumi, 5941101, Japan

Last Updated: 09/26/2026

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Found 25 publications

Integrated Genetic and Biochemical Approach to Patients with Bone Disorders Exhibiting Low Alkaline Phosphatase.

Integrated Genetic and Biochemical Approach to Patients with Bone Disorders Exhibiting Low Alkaline Phosphatase.

Journal: Calcified tissue international
Published: April 13, 2026

Involvement of impaired phosphate production and aberrant extracellular ATP signaling in the pathogenesis of hypophosphatasia: Analysis of ALPL-Knockout human iPS cell models.

Involvement of impaired phosphate production and aberrant extracellular ATP signaling in the pathogenesis of hypophosphatasia: Analysis of ALPL-Knockout human iPS cell models.

Journal: Bone
Published: July 18, 2025

Efficacy of asfotase alfa in a patient with adult-onset hypophosphatasia without obvious bone lesions: a case report with review of literature.

Efficacy of asfotase alfa in a patient with adult-onset hypophosphatasia without obvious bone lesions: a case report with review of literature.

Journal: Endocrine journal
Published: January 29, 2025

Effects of enzyme replacement therapy in sibling cases of hypophosphatasia of varying severities.

Effects of enzyme replacement therapy in sibling cases of hypophosphatasia of varying severities.

Journal: Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology
Published: November 01, 2024

Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.

Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.

Journal: Bone
Published: November 16, 2023

The Effect of Asfotase Alfa on Plasma and Urine Pyrophosphate Levels and Pseudofractures in a Patient With Adult-Onset Hypophosphatasia.

The Effect of Asfotase Alfa on Plasma and Urine Pyrophosphate Levels and Pseudofractures in a Patient With Adult-Onset Hypophosphatasia.

Journal: JBMR plus
Published: August 01, 2023

A case of osteopathia striata with cranial sclerosis with facial nerve palsies.

A case of osteopathia striata with cranial sclerosis with facial nerve palsies.

Journal: Pediatrics international : official journal of the Japan Pediatric Society
Published: April 21, 2023

A unique case of childhood hypophosphatasia caused by a novel heterozygous 51-bp in-frame deletion in the ALPL gene.

A unique case of childhood hypophosphatasia caused by a novel heterozygous 51-bp in-frame deletion in the ALPL gene.

Journal: Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology
Published: March 13, 2023

Growth-related skeletal changes and alterations in phosphate metabolism.

Growth-related skeletal changes and alterations in phosphate metabolism.

Journal: Bone
Published: February 03, 2022

Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression.

Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression.

Journal: Bone
Published: December 24, 2020

Novel mutation in the ALPL gene with a dominant negative effect in a Japanese family.

Novel mutation in the ALPL gene with a dominant negative effect in a Japanese family.

Journal: Journal of bone and mineral metabolism
Published: October 23, 2020

Hypophosphatasia in Japan: ALPL Mutation Analysis in 98 Unrelated Patients.

Hypophosphatasia in Japan: ALPL Mutation Analysis in 98 Unrelated Patients.

Journal: Calcified tissue international
Published: September 12, 2019
Showing 1-12 of 25

Last Updated: 09/26/2026