Last Updated: 09/26/2026
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Found 15 publications
Structural basis of Cdk7 activation by dual T-loop phosphorylation.
Journal: bioRxiv : the preprint server for biology
Published: February 26, 2024
Structural basis of Cdk7 activation by dual T-loop phosphorylation.
Journal: Nature communications
Published: January 10, 2024
The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation.
Journal: The Journal of biological chemistry
Published: July 18, 2023
A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
Journal: Nucleic acids research
Published: January 25, 2023
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.
Journal: Nature communications
Published: April 28, 2021
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.
Journal: European journal of medicinal chemistry
Published: February 07, 2021
Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Journal: Nature communications
Published: December 08, 2016
Structural and Functional Analysis of the Cdk13/Cyclin K Complex.
Journal: Cell reports
Published: July 07, 2015
Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains.
Journal: Cell reports
Published: July 28, 2014
The structure and substrate specificity of human Cdk12/Cyclin K.
Journal: Nature communications
Published: December 06, 2013
Last Updated: 09/26/2026