Karen J. Horsburgh

Little France Crescent
Edinburgh, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 44 publications

Col4a1 mutation in a mouse model of cerebral small vessel disease causes white matter defects that can be modulated by targeting protein folding.

Col4a1 mutation in a mouse model of cerebral small vessel disease causes white matter defects that can be modulated by targeting protein folding.

Journal: Matrix biology : journal of the International Society for Matrix Biology

Published: April 20, 2026

Systematic review and meta-analysis of cognitive assessments used to detect deficits in the bilateral carotid artery stenosis model for vascular cognitive impairment.

Systematic review and meta-analysis of cognitive assessments used to detect deficits in the bilateral carotid artery stenosis model for vascular cognitive impairment.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Published: January 17, 2026

Author Correction: Microglia regulate central nervous system myelin growth and integrity.

Author Correction: Microglia regulate central nervous system myelin growth and integrity.

Journal: Nature

Published: July 03, 2024

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion.

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion.

Journal: Acta neuropathologica communications

Published: January 08, 2024

Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity.

Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity.

Journal: Cell reports

Published: August 18, 2023

Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.

Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.

Journal: Glia

Published: June 02, 2023

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases.

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases.

Journal: Stem cell reports

Published: February 17, 2023

Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke.

Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke.

Journal: Brain pathology (Zurich, Switzerland)

Published: March 02, 2022

Nox2 underpins microvascular inflammation and vascular contributions to cognitive decline.

Nox2 underpins microvascular inflammation and vascular contributions to cognitive decline.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Published: February 01, 2022

Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment.

Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment.

Journal: Frontiers in aging neuroscience

Published: October 02, 2021

Microglia regulate central nervous system myelin growth and integrity.

Microglia regulate central nervous system myelin growth and integrity.

Journal: Nature

Published: June 09, 2021

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease.

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Published: March 18, 2021

Showing 1-12 of 44

Last Updated: 09/26/2026