Karin J. Koolen
Nijmegen, GE, Netherlands
Last Updated: 09/26/2026
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Found 13 publications
Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Journal: Nature
Published: November 29, 2025
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
Journal: PLoS pathogens
Published: July 22, 2024
Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
Journal: SLAS discovery : advancing life sciences R & D
Published: June 08, 2022
Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission.
Journal: PLoS biology
Published: September 02, 2021
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Journal: Nature communications
Published: May 17, 2021
A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages.
Journal: Frontiers in cellular and infection microbiology
Published: December 14, 2018
Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 04, 2018
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Journal: Science translational medicine
Published: January 12, 2018
Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission.
Journal: Scientific reports
Published: July 11, 2017
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Journal: Nature
Published: October 09, 2015
Novel pantothenate derivatives for anti-malarial chemotherapy.
Journal: Malaria journal
Published: December 01, 2014
A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs.
Journal: The Journal of antimicrobial chemotherapy
Published: October 20, 2014
Last Updated: 09/26/2026