Karin Schmidtkunz
Freiburg I. Br
Freiburg, BW, Germany
Freiburg, BW, Germany
Last Updated: 09/26/2026
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Found 31 publications
Soft drug inhibitors for the epigenetic targets lysine-specific demethylase 1 and histone deacetylases.
Journal: Archiv der Pharmazie
Published: June 04, 2024
Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells.
Journal: Archiv der Pharmazie
Published: September 25, 2023
A novel pan-selective bromodomain inhibitor for epigenetic drug design.
Journal: European journal of medicinal chemistry
Published: December 01, 2022
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
Journal: International journal of molecular sciences
Published: May 24, 2022
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Journal: Chembiochem : a European journal of chemical biology
Published: April 01, 2022
Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2.
Journal: Cell reports
Published: July 06, 2021
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Journal: European journal of medicinal chemistry
Published: June 17, 2021
4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines.
Journal: Journal of medicinal chemistry
Published: December 04, 2020
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Journal: European journal of medicinal chemistry
Published: August 19, 2020
Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
Journal: European journal of medicinal chemistry
Published: February 17, 2020
Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases.
Journal: Frontiers in oncology
Published: December 09, 2019
Last Updated: 09/26/2026