Karin Wisskirchen

Munich, BY, Germany

Last Updated: 09/26/2026

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Found 23 publications

Modular delivery of co-stimulatory signals through a PD-1-based immunoswitch receptor improves the functionality of Hepatitis B Virus-specific engineered T cells.

Modular delivery of co-stimulatory signals through a PD-1-based immunoswitch receptor improves the functionality of Hepatitis B Virus-specific engineered T cells.

Journal: Frontiers in immunology

Published: March 02, 2026

Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.

Clinical results of an HBV-specific T-cell receptor-T-cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma treated in an investigator-initiated, interventional trial.

Journal: Gut

Published: April 02, 2025

Correspondence to editorial on "Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting".

Correspondence to editorial on "Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting".

Journal: Clinical and molecular hepatology

Published: September 23, 2024

Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting.

Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting.

Journal: Clinical and molecular hepatology

Published: January 20, 2024

HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx.

HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx.

Journal: JHEP reports : innovation in hepatology

Published: December 03, 2023

Vector-Mediated Delivery of Human Major Histocompatibility Complex-I into Hepatocytes Enables Investigation of T Cell Receptor-Redirected Hepatitis B Virus-Specific T Cells in Mice, and in Macaque Cell Cultures.

Vector-Mediated Delivery of Human Major Histocompatibility Complex-I into Hepatocytes Enables Investigation of T Cell Receptor-Redirected Hepatitis B Virus-Specific T Cells in Mice, and in Macaque Cell Cultures.

Journal: Human gene therapy

Published: September 25, 2023

Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles.

Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles.

Journal: Frontiers in immunology

Published: September 15, 2022

Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins.

Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins.

Journal: Frontiers in immunology

Published: August 26, 2022

Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity.

Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity.

Journal: Cells

Published: September 30, 2021

Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors.

Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors.

Journal: Molecular therapy. Methods & clinical development

Published: July 15, 2021

Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B.

Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B.

Journal: Frontiers in immunology

Published: June 30, 2021

Identification and Characterization of Antigen-Specific CD8+ T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing.

Identification and Characterization of Antigen-Specific CD8+ T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: June 07, 2021

Showing 1-12 of 23

Last Updated: 09/26/2026