Karl Brendel
Paris, France
Last Updated: 09/26/2026
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Found 9 publications
Advances and Further Comparison of Software Tools for Fisher Information Matrix-Based Design Evaluation in Pharmacometrics.
Journal: Pharmaceutical research
Published: November 14, 2025
Population Pharmacokinetics and Pharmacokinetics-Pharmacodynamics Analyses of Elafibranor to Support Dose Selection in Primary Biliary Cholangitis.
Journal: CPT: pharmacometrics & systems pharmacology
Published: October 22, 2025
The Evolving Role of In Vitro-In Vivo Correlation in Model-Informed Drug Development: A Multi-Stakeholder Perspective.
Journal: CPT: pharmacometrics & systems pharmacology
Published: July 04, 2025
Using Fisher Information Matrix to predict uncertainty in covariate effects and power to detect their relevance in Non-Linear Mixed Effect Models in pharmacometrics.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: November 05, 2024
Population pharmacokinetics of liposomal irinotecan in patients with cancer and exposure-safety analyses in patients with metastatic pancreatic cancer.
Journal: CPT: pharmacometrics & systems pharmacology
Published: January 15, 2021
Development and performance of npde for the evaluation of time-to-event models.
Journal: Pharmaceutical research
Published: April 28, 2017
First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours.
Journal: European journal of cancer (Oxford, England : 1990)
Published: April 27, 2017
Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: July 03, 2015
Optimal sampling times for a drug and its metabolite using SIMCYP(®) simulations as prior information.
Journal: Clinical pharmacokinetics
Published: December 06, 2012
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Last Updated: 09/26/2026