Karolien De Bosscher

Gent, VLG, Belgium

Last Updated: 09/26/2026

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Found 101 publications

Nuclear Receptors Shape Sepsis Pathophysiology.

Nuclear Receptors Shape Sepsis Pathophysiology.

Journal: Endocrine reviews

Published: February 24, 2026

A Convenient Laboratory-Scale Synthesis Route Toward the PPARα Agonist Pemafibrate.

A Convenient Laboratory-Scale Synthesis Route Toward the PPARα Agonist Pemafibrate.

Journal: ChemistryOpen

Published: February 19, 2026

RXRα suppression drives hepatic metabolic and immune dysfunction in sepsis.

RXRα suppression drives hepatic metabolic and immune dysfunction in sepsis.

Journal: EMBO molecular medicine

Published: February 17, 2026

Modeling of glucocorticoid resistance in multiple myeloma reveals mechanisms and markers of glucocorticoid resistance.

Modeling of glucocorticoid resistance in multiple myeloma reveals mechanisms and markers of glucocorticoid resistance.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 08, 2025

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.

HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.

Journal: Frontiers in immunology

Published: May 08, 2025

Development of 2- and 3-prenylated quinolines and tetrahydroquinolines with PPAR activity: From hit to lead and a novel pan-PPAR agonist as a potential candidate for metabolic syndrome.

Development of 2- and 3-prenylated quinolines and tetrahydroquinolines with PPAR activity: From hit to lead and a novel pan-PPAR agonist as a potential candidate for metabolic syndrome.

Journal: Bioorganic chemistry

Published: December 23, 2024

CCR1 inhibition sensitizes multiple myeloma cells to glucocorticoid therapy.

CCR1 inhibition sensitizes multiple myeloma cells to glucocorticoid therapy.

Journal: Pharmacological research

Published: December 19, 2024

Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain.

Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain.

Journal: European journal of medicinal chemistry

Published: October 23, 2024

PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression.

PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression.

Journal: Metabolism: clinical and experimental

Published: October 15, 2024

Exploring protein conformations with limited proteolysis coupled to mass spectrometry.

Exploring protein conformations with limited proteolysis coupled to mass spectrometry.

Journal: Trends in biochemical sciences

Published: August 29, 2024

NCOR1/2 and glucocorticoid receptor orchestrate hepatic function.

NCOR1/2 and glucocorticoid receptor orchestrate hepatic function.

Journal: Nature metabolism

Published: April 15, 2024

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.

Journal: EMBO molecular medicine

Published: March 26, 2024

Showing 1-12 of 101

Last Updated: 09/26/2026