Karolien Grauwen

Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 8 publications

NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.

NLRP3 inflammasome activation and pyroptosis are dispensable for tau pathology.

Journal: Frontiers in aging neuroscience

Published: July 03, 2024

Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.

Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.

Journal: EMBO molecular medicine

Published: May 23, 2024

Structural basis for the oligomerization-facilitated NLRP3 activation.

Structural basis for the oligomerization-facilitated NLRP3 activation.

Journal: Nature communications

Published: June 08, 2023

IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.

IP-LC-MSMS Enables Identification of Three Tau O-GlcNAcylation Sites as O-GlcNAcase Inhibition Pharmacodynamic Readout in Transgenic Mice Overexpressing Human Tau.

Journal: Journal of proteome research

Published: March 08, 2023

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells.

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells.

Journal: Nanoscale

Published: April 22, 2021

Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.

Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.

Journal: Journal of chromatography. A

Published: March 19, 2021

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.

Journal: Brain : a journal of neurology

Published: February 21, 2019

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines.

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines.

Journal: Cytokine

Published: April 18, 2012

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Last Updated: 09/26/2026