Karsten Tillack

Hamburg, HH 22419, Germany

Last Updated: 09/26/2026

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Found 9 publications

Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors.

Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors.

Journal: Bioorganic & medicinal chemistry letters
Published: February 19, 2025

Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.

Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.

Journal: JCI insight
Published: May 10, 2022

Meso scale discovery-based assays for the detection of aggregated huntingtin.

Meso scale discovery-based assays for the detection of aggregated huntingtin.

Journal: PloS one
Published: October 12, 2018

Correction to: Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.

Correction to: Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.

Journal: Cell death & disease
Published: May 27, 2018

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.

Journal: Nature medicine
Published: February 28, 2017

Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.

Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.

Journal: Cell death & disease
Published: March 28, 2016

An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice.

An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice.

Journal: PloS one
Published: February 16, 2015

Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study.

Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study.

Journal: PloS one
Published: November 24, 2014

Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit.

Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit.

Journal: Neuron
Published: May 01, 2012
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Last Updated: 09/26/2026