Kate Jackson-Smith

Farmington Place
Newcastle Upon Tyne, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 18 publications

Properdin deficiency or anti-properdin treatment ameliorates disease in the C3 gain-of-function mouse model of atypical haemolytic uraemic syndrome.

Properdin deficiency or anti-properdin treatment ameliorates disease in the C3 gain-of-function mouse model of atypical haemolytic uraemic syndrome.

Journal: Frontiers in immunology

Published: March 11, 2026

Biallelic pathogenic variants in EXOSC3 mediate renal thrombotic microangiopathy of the kidney.

Biallelic pathogenic variants in EXOSC3 mediate renal thrombotic microangiopathy of the kidney.

Journal: Kidney international

Published: February 10, 2026

The membrane attack complex drives thrombotic microangiopathy in complement mediated atypical hemolytic uremic syndrome.

The membrane attack complex drives thrombotic microangiopathy in complement mediated atypical hemolytic uremic syndrome.

Journal: Kidney international

Published: December 05, 2023

Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome.

Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome.

Journal: Transplantation

Published: November 22, 2022

Alternative pathway activation in pregnancy, a measured amount "complements" a successful pregnancy, too much results in adverse events.

Alternative pathway activation in pregnancy, a measured amount "complements" a successful pregnancy, too much results in adverse events.

Journal: Immunological reviews

Published: November 15, 2022

Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.

Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.

Journal: Blood

Published: October 27, 2022

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.

Journal: Frontiers in immunology

Published: August 26, 2022

Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice.

Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice.

Journal: Frontiers in immunology

Published: August 03, 2021

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD.

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD.

Journal: Frontiers in immunology

Published: September 02, 2020

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.

Journal: Human molecular genetics

Published: August 14, 2020

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.

Journal: Kidney international

Published: November 14, 2019

Targeting properdin in the treatment of atypical haemolytic uraemic syndrome: better than eculizumab?

Targeting properdin in the treatment of atypical haemolytic uraemic syndrome: better than eculizumab?

Journal: Annals of translational medicine

Published: January 08, 2019

Showing 1-12 of 18

Last Updated: 09/26/2026