Kathryn L. Kavanagh

Oxford, ENG OX37DQ, United Kingdom

Last Updated: 09/26/2026

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Found 29 publications

A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.

A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase.

Journal: ACS catalysis

Published: January 07, 2019

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.

Journal: Bone

Published: June 12, 2015

Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.

Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.

Journal: Chemico-biological interactions

Published: September 11, 2014

Ribosomal oxygenases are structurally conserved from prokaryotes to humans.

Ribosomal oxygenases are structurally conserved from prokaryotes to humans.

Journal: Nature

Published: September 30, 2013

Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid.

Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid.

Journal: The Journal of biological chemistry

Published: July 20, 2012

Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.

Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.

Journal: BMC structural biology

Published: March 22, 2012

Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates.

Journal: The Journal of biological chemistry

Published: November 30, 2011

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming.

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 22, 2011

Structure and mechanism of human UDP-glucose 6-dehydrogenase.

Structure and mechanism of human UDP-glucose 6-dehydrogenase.

Journal: The Journal of biological chemistry

Published: April 20, 2011

The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity.

The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity.

Journal: The Biochemical journal

Published: October 30, 2010

UDP-glucose dehydrogenase: structure and function of a potential drug target.

UDP-glucose dehydrogenase: structure and function of a potential drug target.

Journal: Biochemical Society transactions

Published: September 25, 2010

Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.

Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.

Journal: Journal of molecular biology

Published: August 05, 2010

Showing 1-12 of 29

Last Updated: 09/26/2026