Katleen Craessaerts

Leuven, VLG, Belgium

Last Updated: 09/26/2026

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Found 20 publications

The Curious Case of a Heterozygous Loss-of-Function PSEN1 variant associated with Early-Onset Alzheimer's Disease.

The Curious Case of a Heterozygous Loss-of-Function PSEN1 variant associated with Early-Onset Alzheimer's Disease.

Journal: Research square
Published: September 05, 2025

The curious case of a heterozygous loss-of-function PSEN1 variant associated with early-onset Alzheimer's disease.

The curious case of a heterozygous loss-of-function PSEN1 variant associated with early-onset Alzheimer's disease.

Journal: Molecular neurodegeneration advances
Published: July 26, 2025

Human microglial transitions at the Aβ-tau inflection point associate with divergent pathways to dementia and resilience.

Human microglial transitions at the Aβ-tau inflection point associate with divergent pathways to dementia and resilience.

Journal: Nature medicine
Published: July 11, 2025

The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia.

The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia.

Journal: Nature neuroscience
Published: July 30, 2024

Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.

Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.

Journal: Cell reports
Published: May 16, 2024

NACC2, a molecular effector of miR-132 regulation at the interface between adult neurogenesis and Alzheimer's disease.

NACC2, a molecular effector of miR-132 regulation at the interface between adult neurogenesis and Alzheimer's disease.

Journal: Scientific reports
Published: May 03, 2024

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.

MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.

Journal: Science (New York, N.Y.)
Published: September 14, 2023

Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins.

Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins.

Journal: iScience
Published: September 10, 2023

Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.

Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.

Journal: Nature neuroscience
Published: October 06, 2022

Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models.

Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models.

Journal: eNeuro
Published: July 25, 2022

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.

Journal: Cell reports
Published: May 17, 2022

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Journal: Cell stem cell
Published: March 17, 2021
Showing 1-12 of 20

Last Updated: 09/26/2026