Kaushik Ghosh - Publications

Discovery of Non-prostanoid EP4 Agonists for the Treatment of Inflammatory Bowel Disease.

Journal: Journal of medicinal chemistry

Published: April 03, 2026

Investigating organic cation transporter 1 in drug interactions: New findings from in vitro and in vivo cynomolgus monkey studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: June 23, 2025

Mezigdomide combined with bortezomib disrupts the cell cycle and elicits superior antitumor effects in multiple myeloma.

Journal: Blood neoplasia

Published: December 02, 2024

Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione.

Journal: Journal of medicinal chemistry

Published: August 05, 2024

Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design.

Journal: Bioorganic & medicinal chemistry

Published: November 13, 2023

Discovery of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of adaptor protein 2-associated kinase 1 for the treatment of pain.

Journal: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents

Published: March 26, 2023

In vivo antioxidant and hypoglycaemic potentials of Rivina humilis extract against streptozotocin induced diabetes and its complications in wistar rats.

Journal: Journal of diabetes and metabolic disorders

Published: October 11, 2022

Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.

Journal: Journal of medicinal chemistry

Published: August 15, 2022

Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors.

Journal: Journal of medicinal chemistry

Published: February 16, 2022

Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.

Journal: Journal of medicinal chemistry

Published: May 14, 2021

Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.

Journal: Glycobiology

Published: February 26, 2021

Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.

Journal: Journal of medicinal chemistry

Published: November 23, 2020