Kazue Nakashima-Hisaoka

Higashihiroshima, Japan

Last Updated: 09/26/2026

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Found 73 publications

LPA4 in the spinal dorsal horn is a potential therapeutic target for inflammatory pain and neuropathic mechanical hypersensitivity.

LPA4 in the spinal dorsal horn is a potential therapeutic target for inflammatory pain and neuropathic mechanical hypersensitivity.

Journal: iScience

Published: January 21, 2026

Tricyclic antidepressant amitriptyline potentiates brain-derived neurotrophic factor expression mediated by PKC delta-NF-kappa B signaling in primary cultured astrocytes with connexin43-knockdown.

Tricyclic antidepressant amitriptyline potentiates brain-derived neurotrophic factor expression mediated by PKC delta-NF-kappa B signaling in primary cultured astrocytes with connexin43-knockdown.

Journal: Neurochemistry international

Published: September 17, 2025

Age-related brain functional changes and microglia

Age-related brain functional changes and microglia

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica

Published: August 31, 2025

Preventive effect of RAGE antagonists on distal infraorbital nerve injury-induced pain behaviors of male and female mice.

Preventive effect of RAGE antagonists on distal infraorbital nerve injury-induced pain behaviors of male and female mice.

Journal: Biochemical pharmacology

Published: May 20, 2025

Mitochondrial dysfunction exacerbates inflammatory responses via the JNK/p38-AP-1 pathway in primary cultured chondrocytes.

Mitochondrial dysfunction exacerbates inflammatory responses via the JNK/p38-AP-1 pathway in primary cultured chondrocytes.

Journal: International immunopharmacology

Published: April 15, 2025

Voluntary exercise prevents and eradicates anxiety-like behavior by influencing parvalbumin-positive neurons, perineuronal nets, and microglia activation in corticolimbic regions of neuropathic pain rats.

Voluntary exercise prevents and eradicates anxiety-like behavior by influencing parvalbumin-positive neurons, perineuronal nets, and microglia activation in corticolimbic regions of neuropathic pain rats.

Journal: Neurobiology of pain (Cambridge, Mass.)

Published: January 26, 2025

Hippocampal microglial activation induces cognitive impairment and allodynia through neuronal plasticity changes in male mice with neuropathic pain.

Hippocampal microglial activation induces cognitive impairment and allodynia through neuronal plasticity changes in male mice with neuropathic pain.

Journal: Behavioural brain research

Published: January 07, 2025

Aging-related dysregulation of energy metabolism and mitochondrial dynamics in microglia.

Aging-related dysregulation of energy metabolism and mitochondrial dynamics in microglia.

Journal: Journal of clinical biochemistry and nutrition

Published: November 27, 2024

Intranasal Treatment with Cannabinoid 2 Receptor Agonist HU-308 Ameliorates Cold Sensitivity in Mice with Traumatic Trigeminal Neuropathic Pain.

Intranasal Treatment with Cannabinoid 2 Receptor Agonist HU-308 Ameliorates Cold Sensitivity in Mice with Traumatic Trigeminal Neuropathic Pain.

Journal: Cells

Published: September 03, 2024

Microglial α7-Nicotinic Acetylcholine Receptors Are Expressed in Mitochondria Rather Than on the Plasma Membrane: Roles in Mitochondrial Function.

Microglial α7-Nicotinic Acetylcholine Receptors Are Expressed in Mitochondria Rather Than on the Plasma Membrane: Roles in Mitochondrial Function.

Journal: Journal of neurochemistry

Published: July 22, 2024

Glucocorticoids induce HMGB1 release in primary cultured rat cortical microglia.

Glucocorticoids induce HMGB1 release in primary cultured rat cortical microglia.

Journal: Neuroscience

Published: June 30, 2024

Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy.

Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy.

Journal: Biological & pharmaceutical bulletin

Published: January 21, 2024

Showing 1-12 of 73

Last Updated: 09/26/2026