Kazuhiko Nakatani

Ibaraki, 5670047, Japan

Last Updated: 09/26/2026

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Found 99 publications

NMR analysis of interaction between RNA structure elements and small molecules: evaluation of RNA libraries and confirmation by two more molecules.

NMR analysis of interaction between RNA structure elements and small molecules: evaluation of RNA libraries and confirmation by two more molecules.

Journal: Journal of biochemistry
Published: March 15, 2026

Small Molecule Modulation of APOBEC3A-Catalyzed Cytosine Deamination in CCG Repeat Deoxyribonucleic Acid via Stabilization of Hairpin Structures.

Small Molecule Modulation of APOBEC3A-Catalyzed Cytosine Deamination in CCG Repeat Deoxyribonucleic Acid via Stabilization of Hairpin Structures.

Journal: Biochemistry
Published: December 04, 2025

Identification and structural insights into RNA motifs targeted by a CAG repeat DNA-binding small molecule.

Identification and structural insights into RNA motifs targeted by a CAG repeat DNA-binding small molecule.

Journal: Chemical science
Published: July 15, 2025

Interventionally targeting somatic CAG expansions can be a rapid disease-modifying therapeutic avenue: Preclinical evidence.

Interventionally targeting somatic CAG expansions can be a rapid disease-modifying therapeutic avenue: Preclinical evidence.

Journal: bioRxiv : the preprint server for biology
Published: May 07, 2025

Naphthyridine carbamate dimer ligand induces formation of Z-RNA-like fold of disease-related RNA and exhibits a molecular glue characteristics in crystal lattice formation.

Naphthyridine carbamate dimer ligand induces formation of Z-RNA-like fold of disease-related RNA and exhibits a molecular glue characteristics in crystal lattice formation.

Journal: Nucleic acids research
Published: April 17, 2025

NMR analysis of interaction between RNA structure elements and small molecules.

NMR analysis of interaction between RNA structure elements and small molecules.

Journal: Journal of biochemistry
Published: February 24, 2025

Structure-Binding Relationship of 2-Amino-1,8-Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition.

Structure-Binding Relationship of 2-Amino-1,8-Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Published: February 02, 2025

The role of spatial arrangement of aromatic rings on the binding of N,N'-diheteroaryl guanidine ligands to the G2C4/G2C4 motif DNA.

The role of spatial arrangement of aromatic rings on the binding of N,N'-diheteroaryl guanidine ligands to the G2C4/G2C4 motif DNA.

Journal: Physical chemistry chemical physics : PCCP
Published: January 27, 2025

Studies on in vitro modulatory effects to base excision repair enzymes induced by small molecule binding to Deaminated CAG repeat hairpin.

Studies on in vitro modulatory effects to base excision repair enzymes induced by small molecule binding to Deaminated CAG repeat hairpin.

Journal: Bioorganic & medicinal chemistry letters
Published: November 25, 2024

Involvement of lncRNA MIR205HG in idiopathic pulmonary fibrosis and IL-33 regulation via Alu elements.

Involvement of lncRNA MIR205HG in idiopathic pulmonary fibrosis and IL-33 regulation via Alu elements.

Journal: JCI insight
Published: September 20, 2024

The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding.

The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding.

Journal: Bioorganic & medicinal chemistry letters
Published: August 05, 2024

Enhancing Binding Affinity to CGG/CGG Triad: Optimizing Naphthyridine Carbamate Dimer Derivatives with Varied Linker Lengths.

Enhancing Binding Affinity to CGG/CGG Triad: Optimizing Naphthyridine Carbamate Dimer Derivatives with Varied Linker Lengths.

Journal: ChemMedChem
Published: May 07, 2024
Showing 1-12 of 99

Last Updated: 09/26/2026