Kazuko Yonemori

Fujisawa, 2518555, Japan

Last Updated: 09/26/2026

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Found 14 publications

Discovery of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 Main Protease through Computer-Aided Drug Design.

Discovery of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 Main Protease through Computer-Aided Drug Design.

Journal: Journal of medicinal chemistry

Published: October 12, 2025

Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole.

Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole.

Journal: Structure (London, England : 1993)

Published: October 19, 2020

Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist.

Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist.

Journal: Journal of medicinal chemistry

Published: March 07, 2018

Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.

Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.

Journal: Bioorganic & medicinal chemistry

Published: December 26, 2017

Discovery of orally efficacious RORγt inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds.

Discovery of orally efficacious RORγt inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds.

Journal: Bioorganic & medicinal chemistry

Published: October 11, 2017

Identification of novel quinazolinedione derivatives as RORγt inverse agonist.

Identification of novel quinazolinedione derivatives as RORγt inverse agonist.

Journal: Bioorganic & medicinal chemistry

Published: October 09, 2017

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.

Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.

Journal: Journal of medicinal chemistry

Published: June 07, 2017

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d.

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d.

Journal: ACS medicinal chemistry letters

Published: March 23, 2017

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.

Journal: Bioorganic & medicinal chemistry letters

Published: March 14, 2017

Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation.

Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation.

Journal: Biochemical and biophysical research communications

Published: February 28, 2017

Farnesoid X receptor antagonist exacerbates dyslipidemia in mice.

Farnesoid X receptor antagonist exacerbates dyslipidemia in mice.

Journal: Pharmacological reports : PR

Published: February 07, 2017

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.

Journal: Bioorganic & medicinal chemistry

Published: February 01, 2017

Showing 1-12 of 14

Last Updated: 09/26/2026