Last Updated: 09/26/2026
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Found 18 publications
A Melanocortin-4 Receptor Agonist Induces Skin and Hair Pigmentation in Patients with Monogenic Mutations in the Leptin-Melanocortin Pathway.
Journal: Skin pharmacology and physiology
Published: October 21, 2020
Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
Journal: The Journal of clinical endocrinology and metabolism
Published: January 31, 2018
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.
Journal: Nature medicine
Published: December 09, 2017
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.
Journal: Molecular metabolism
Published: May 26, 2017
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
Journal: The New England journal of medicine
Published: July 29, 2016
Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Published: February 17, 2015
RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.
Journal: The Journal of clinical endocrinology and metabolism
Published: February 13, 2015
Diary of hot flashes reported upon occurrence: results of a randomized double-blind study of raloxifene, placebo, and paroxetine.
Journal: Menopause (New York, N.Y.)
Published: February 27, 2014
Randomized controlled phase Ib study of ghrelin agonist, RM-131, in type 2 diabetic women with delayed gastric emptying: pharmacokinetics and pharmacodynamics.
Journal: Diabetes care
Published: September 11, 2012
Last Updated: 09/26/2026