Kelvin Cain

Tennis Court Road
Cambridge, ENG CB21QR, United Kingdom

Last Updated: 09/26/2026

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Found 33 publications

The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors.

The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors.

Journal: Biology direct
Published: April 01, 2023

Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells.

Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells.

Journal: International journal of molecular sciences
Published: May 31, 2022

Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.

Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.

Journal: Molecular cell
Published: February 09, 2021

Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.

Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.

Journal: Scientific reports
Published: September 21, 2020

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.

Journal: Nature communications
Published: September 10, 2020

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol.

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol.

Journal: Cell death and differentiation
Published: May 15, 2020

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.

Journal: Nucleic acids research
Published: April 20, 2020

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Journal: Genome biology
Published: July 16, 2019

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.

Journal: Nucleic acids research
Published: November 22, 2018

NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair.

NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair.

Journal: Cell reports
Published: June 17, 2018

Identification of the RNA polymerase I-RNA interactome.

Identification of the RNA polymerase I-RNA interactome.

Journal: Nucleic acids research
Published: April 24, 2018

PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair.

PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair.

Journal: Nature communications
Published: August 11, 2017
Showing 1-12 of 33

Last Updated: 09/26/2026