Ken-ichi I. Hosoya

Toyama, Japan

Last Updated: 09/26/2026

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Found 117 publications

Blood-Retinal Barrier Drug Transport: Aiming to Develop Oral Administration for Retinal Diseases

Blood-Retinal Barrier Drug Transport: Aiming to Develop Oral Administration for Retinal Diseases

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Published: August 03, 2026

Cellular expression and subcellular localization of autotaxin, a lysophosphatidic acid-generating enzyme, in the adult and developing mouse brain.

Cellular expression and subcellular localization of autotaxin, a lysophosphatidic acid-generating enzyme, in the adult and developing mouse brain.

Journal: Neuroscience research

Published: December 25, 2025

Identification of Rat Monocarboxylate Transporter 9 as a Low-Affinity Transporter of 1-Methyl-4-phenylpyridinium and Amantadine.

Identification of Rat Monocarboxylate Transporter 9 as a Low-Affinity Transporter of 1-Methyl-4-phenylpyridinium and Amantadine.

Journal: Biological & pharmaceutical bulletin

Published: December 21, 2025

Role of P-glycoprotein in attenuation of retinal amyloid-β peptide (1-40) clearance across the rat inner blood-retinal barrier induced by lipopolysaccharide.

Role of P-glycoprotein in attenuation of retinal amyloid-β peptide (1-40) clearance across the rat inner blood-retinal barrier induced by lipopolysaccharide.

Journal: Experimental eye research

Published: August 26, 2025

Involvement of monocarboxylate transporter 7 in taurine efflux transport from rat retinal pericytes and capillary endothelial cells.

Involvement of monocarboxylate transporter 7 in taurine efflux transport from rat retinal pericytes and capillary endothelial cells.

Journal: Microvascular research

Published: July 01, 2025

L-Type amino acid transporter 1-mediated developmental change of cerebral gabapentin distribution across the rat blood-brain barrier.

L-Type amino acid transporter 1-mediated developmental change of cerebral gabapentin distribution across the rat blood-brain barrier.

Journal: Drug metabolism and pharmacokinetics

Published: April 08, 2025

Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide.

Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide.

Journal: Pharmaceutical research

Published: November 22, 2024

Upregulation of P-Glycoprotein and Breast Cancer Resistance Protein Activity in Newly Developed in Vitro Rat Blood-Brain Barrier Spheroids Using Advanced Glycation End-Products.

Upregulation of P-Glycoprotein and Breast Cancer Resistance Protein Activity in Newly Developed in Vitro Rat Blood-Brain Barrier Spheroids Using Advanced Glycation End-Products.

Journal: Biological & pharmaceutical bulletin

Published: November 17, 2024

Neuroprotective effects of compounds interacting with carrier-mediated amantadine transport across the blood-retinal barrier in rats.

Neuroprotective effects of compounds interacting with carrier-mediated amantadine transport across the blood-retinal barrier in rats.

Journal: Journal of pharmacological sciences

Published: September 12, 2024

In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model.

In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model.

Journal: Drug metabolism and pharmacokinetics

Published: July 17, 2024

Blood-to-Testis Transport of Ribavirin Involves Carrier-Mediated Processes at the Blood-Testis Barrier.

Blood-to-Testis Transport of Ribavirin Involves Carrier-Mediated Processes at the Blood-Testis Barrier.

Journal: Journal of pharmaceutical sciences

Published: February 06, 2024

Molecular Mechanism of SLC6A8 Dysfunction with c.1699T > C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes.

Molecular Mechanism of SLC6A8 Dysfunction with c.1699T > C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes.

Journal: Biological & pharmaceutical bulletin

Published: January 17, 2024

Showing 1-12 of 117

Last Updated: 09/26/2026